ZFIN ID: ZDB-FIG-140709-38
Feng et al., 2010 - Dhrs3a regulates retinoic acid biosynthesis through a feedback inhibition mechanism. Developmental Biology   338(1):1-14 Full text @ Dev. Biol.
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Fish:
Conditions:
Anatomical Terms:
Stage: 1-4 somites

Fig. 5 dhrs3a is expressed in an RA-dependent manner. RNA in situ hybridization of dhrs3a (blue) and egr2b (red in A–C). (A) DMSO-treated; (B) 10 µM DEAB-treated, (C) 0.33 µm RA-treated. (D) wild-type untreated, (E) aldh1a2i26/i26/neckless mutant, (F) cyp26a1rw716/rw716/giraffe mutant. Anterior is to the left in all panels.

Gene Expression Details
Gene Antibody Fish Conditions Stage Qualifier Anatomy Assay
dhrs3a AB control 1-4 somites lateral plate mesoderm ISH
1-4 somites mesoderm ISH
AB standard conditions 1-4 somites lateral plate mesoderm ISH
1-4 somites mesoderm ISH
AB chemical treatment: 4-(diethylamino)benzaldehyde 1-4 somites Not Detected whole organism ISH
AB chemical treatment: all-trans-retinoic acid 1-4 somites whole organism ISH
aldh1a2i26/i26 standard conditions 1-4 somites Not Detected whole organism ISH
cyp26a1rw716/rw716 standard conditions 1-4 somites lateral plate mesoderm ISH
1-4 somites mesoderm ISH
egr2b AB control 1-4 somites presumptive rhombomere 3 ISH
1-4 somites presumptive rhombomere 5 ISH
AB chemical treatment: 4-(diethylamino)benzaldehyde 1-4 somites hindbrain neural plate ISH
AB chemical treatment: all-trans-retinoic acid 1-4 somites Not Detected hindbrain neural plate ISH
Antibody Labeling Details No data available
Phenotype Details No data available
Acknowledgments:
ZFIN wishes to thank the journal Developmental Biology for permission to reproduce figures from this article. Please note that this material may be protected by copyright.

Reprinted from Developmental Biology, 338(1), Feng, L., Hernandez, R.E., Waxman, J.S., Yelon, D., and Moens, C.B., Dhrs3a regulates retinoic acid biosynthesis through a feedback inhibition mechanism, 1-14, Copyright (2010) with permission from Elsevier. Full text @ Dev. Biol.