ZFIN ID: ZDB-FIG-121220-7
Ota et al., 2012 - NLK positively regulates Wnt/beta-catenin signalling by phosphorylating LEF1 in neural progenitor cells. The EMBO journal   31(8):1904-1915 Full text @ EMBO J.
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Fish:
Knockdown Reagents:
Anatomical Terms:
Stage Range: Prim-15 to Protruding-mouth
PHENOTYPE:
Fish:
Knockdown Reagents:
Observed In:
Stage Range: Prim-15 to Protruding-mouth

Fig. 2 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
Kaede rw0130aTg standard conditions Protruding-mouth neuron IFL
rw0130aTg + MO1-nlk2 standard conditions Protruding-mouth neuron IFL
rw0130aTg + MO1-nlk2 + MO4-tp53 standard conditions Protruding-mouth neuron IFL
rw0130aTg + MO2-lef1 standard conditions Protruding-mouth neuron IFL
rw0130aTg + MO2-lef1 + MO4-tp53 standard conditions Protruding-mouth neuron IFL
rw0130aTg + MO2-nlk2 standard conditions Protruding-mouth neuron IFL
rw0130aTg + MO2-nlk2 + MO4-tp53 standard conditions Protruding-mouth neuron IFL
zic2a WT standard conditions Prim-15 brain ISH
WT + MO1-nlk2 standard conditions Prim-15 brain ISH
WT + MO2-lef1 standard conditions Prim-15 brain ISH
WT + MO2-nlk2 standard conditions Prim-15 brain ISH
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
WT + MO1-nlk2 standard conditions Prim-15 cell proliferation in midbrain decreased occurrence, abnormal
WT + MO2-lef1 standard conditions Prim-15 cell proliferation in midbrain decreased occurrence, abnormal
WT + MO2-nlk2 standard conditions Prim-15 cell proliferation in midbrain decreased occurrence, abnormal
rw0130aTg + MO1-nlk2 standard conditions Protruding-mouth midbrain development disrupted, abnormal
Protruding-mouth optic tectum decreased size, abnormal
rw0130aTg + MO1-nlk2 + MO4-tp53 standard conditions Protruding-mouth midbrain development disrupted, abnormal
Protruding-mouth optic tectum decreased size, abnormal
rw0130aTg + MO2-lef1 standard conditions Protruding-mouth midbrain development disrupted, abnormal
Protruding-mouth optic tectum decreased size, abnormal
rw0130aTg + MO2-lef1 + MO4-tp53 standard conditions Protruding-mouth midbrain development disrupted, abnormal
Protruding-mouth optic tectum decreased size, abnormal
rw0130aTg + MO2-nlk2 standard conditions Protruding-mouth midbrain development disrupted, abnormal
Protruding-mouth optic tectum decreased size, abnormal
rw0130aTg + MO2-nlk2 + MO4-tp53 standard conditions Protruding-mouth midbrain development disrupted, abnormal
Protruding-mouth optic tectum decreased size, abnormal
Full text @ EMBO J.