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General Information
ZIRC
ZFIN ID: ZDB-FISH-150901-10037
Fish name: WT + MO2-lef1
Genotype: WT
Targeting Reagent: MO2-lef1
HUMAN DISEASE MODELED by WT + MO2-lef1
No data available
GENE EXPRESSION
Gene expression in WT + MO2-lef1
RNA expression
Expressed Gene Structure Conditions Figures
ascl1a standard conditions Fig. 4 with image from Lee et al., 2006
barhl2 standard conditions Fig. S6 with image from Russek-Blum et al., 2008
dlx2a standard conditions Fig. 4 with image from Lee et al., 2006
dmbx1a standard conditions Fig. 3 with image from Bonkowsky et al., 2008
emx2 standard conditions Fig. 3 with image from Lee et al., 2006
foxp2 standard conditions Fig. 3 with imageFig. S1 with image from Bonkowsky et al., 2008
isl1 standard conditions Fig. 4 with image from Lee et al., 2006
lef1 standard conditions Fig. S1 with image from Lee et al., 2006
neurog1 standard conditions Fig. 4 with image from Lee et al., 2006
nkx2.4b standard conditions Fig. 3 with image from Lee et al., 2006
olig2 standard conditions Fig. 4 with image from Lee et al., 2006
rx3 standard conditions Fig. 3 with image from Lee et al., 2006
slc6a3 standard conditions Fig. 8 with image from Russek-Blum et al., 2008
sox3 standard conditions Fig. 4 with image from Lee et al., 2006
th standard conditions Fig. S6 with image from Russek-Blum et al., 2008
zic2a standard conditions Fig. 2 from Ota et al., 2012
Fig. 6 with image from Nyholm et al., 2007
Protein expression No data available
Reporter gene expression No data available
PHENOTYPE
Phenotype in WT + MO2-lef1
Phenotype Conditions Figures
brain wholly posterioralized, abnormal standard conditions Fig. 6 with image from Nyholm et al., 2007
cartilage morphogenesis disrupted, abnormal standard conditions Fig. 1 from Ishitani et al., 2005
cell proliferation in midbrain decreased occurrence, abnormal standard conditions Fig. 2 from Ota et al., 2012
cranial cartilage morphology, abnormal standard conditions Fig. 1 from Ishitani et al., 2005
diencephalon dopaminergic neuron increased amount, abnormal standard conditions Fig. 8 with imageFig. S6 with image from Russek-Blum et al., 2008
dorsal root ganglion decreased amount, abnormal standard conditions Fig. 1 from Ishitani et al., 2005
dorsal root ganglion mislocalised, abnormal standard conditions Fig. 1 from Ishitani et al., 2005
forebrain neuron development disrupted, abnormal standard conditions Fig. 4 with image from Lee et al., 2006
hypothalamus axon decreased amount, abnormal standard conditions Fig. 5 with image from Lee et al., 2006
hypothalamus neuron decreased amount, abnormal standard conditions Fig. 5 with image from Lee et al., 2006
hypothalamus neuron morphology, abnormal standard conditions Fig. 4 with image from Lee et al., 2006
hypothalamus cell differentiation disrupted, abnormal standard conditions Fig. 5 with image from Lee et al., 2006
mandibular arch skeleton decreased size, abnormal standard conditions Fig. 1 from Ishitani et al., 2005
midbrain morphology, abnormal standard conditions Fig. 6 with image from Nyholm et al., 2007
neural crest cell development disrupted, abnormal standard conditions Fig. 1 from Ishitani et al., 2005

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