ZFIN ID: ZDB-FIG-110720-48
Patil et al., 2011 - Functional Analysis of Retinitis Pigmentosa 2 (RP2) Protein Reveals Variable Pathogenic Potential of Disease-Associated Missense Variants. PLoS One   6(6):e21379 Full text @ PLoS One
ADDITIONAL FIGURES
PHENOTYPE:
Fish:
Knockdown Reagent:
Observed In:
Stage: Day 4

Fig. S1

RP2 is expressed in both rod and cone photoreceptors. Immunofluorescence analysis of 4 dpf zebrafish embryos injected SNC-MO and rp2-MO was performed using anti-rhodopsin (1D4) antibody or PNA (red). Nuclei are stained with DAPI (blue). RPE: retinal pigmented epithelium; OS: outer segment; IS: inner segment; ONL: outer nuclear layer; INL: inner nuclear layer; GCL: ganglion cell layer.

Gene Expression DetailsNo data available
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
WT + MO3-rp2 standard conditions Day 4 photoreceptor cell development disrupted, abnormal
Day 4 photoreceptor cell morphogenesis disrupted, abnormal
Day 4 photoreceptor cell outer segment organization disrupted, abnormal
Acknowledgments:
ZFIN wishes to thank the journal PLoS One for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Full text @ PLoS One