ZFIN ID: ZDB-FIG-100616-97
Insinna et al., 2010 - Analysis of a zebrafish dync1h1 mutant reveals multiple functions for cytoplasmic dynein 1 during retinal photoreceptor development. Neural Development   5:12 Full text @ Neural Dev.
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Gene:
Antibodies:
Fish:
Anatomical Terms:
Stage: Day 4
PHENOTYPE:
Fish:
Observed In:
Stage: Day 4

Fig. 6 Immunolocalization of Dync1h1 in developing photoreceptors. (A-E) Cryosections of the photoreceptor layer from wild-type retina (A, C, E) or cnb mutant retina (B, D) each at 4 dpf. Antisera directed against two different regions of Dync1h1 was used: (A, B) anti-human DYNC1H1 (huDYNC1H1; carboxy-terminal 400 amino acids) and (C, D) anti-rat Dync1h1 (amino acids 4,320 to 4,644). Primary antibodies were omitted in (E). For each panel, the fluorescent image is shown on the left and the transmitted light image on the right. CB, cell body; OS, outer segment; RPE, retina pigment epithelium; SR, synaptic region.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
dync1h1 Ab3-dync1h1 WT standard conditions Day 4 eye photoreceptor cell IHC
Ab2-dync1h1 Day 4 eye photoreceptor cell IHC
Ab3-dync1h1 Day 4 photoreceptor outer segment layer IHC
Ab2-dync1h1 Day 4 photoreceptor outer segment layer IHC
Ab3-dync1h1 Day 4 retinal photoreceptor layer IHC
Ab2-dync1h1 Day 4 retinal photoreceptor layer IHC
Ab2-dync1h1 dync1h1mw20/mw20 standard conditions Day 4 retinal photoreceptor layer IHC
Ab3-dync1h1 Day 4 retinal photoreceptor layer IHC
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
dync1h1mw20/mw20 standard conditions Day 4 retinal photoreceptor layer physical object quality, abnormal
Acknowledgments:
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