ZFIN ID: ZDB-FIG-081106-8
Rotllant et al., 2008 - Sparc (Osteonectin) functions in morphogenesis of the pharyngeal skeleton and inner ear. Matrix biology : journal of the International Society for Matrix Biology   27(6):561-572 Full text @ Matrix Biol.
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Gene: sparc
Fish: AB
Anatomical Terms: floor plate, otic placode, pronephros, ventral fin fold
Stage Range: 10-13 somites to Protruding-mouth
PHENOTYPE:
Fish: AB + MO2-sparc, AB + MO3-sparc
Knockdown Reagents: MO2-sparc, MO3-sparc
Observed In: ceratobranchial cartilage, ceratohyal cartilage, chondrocranium cartilage, Meckel's cartilage, pectoral fin (all 8) expand
Stage Range: Day 4 to Days 7-13

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Gene Expression Details
Gene Antibody Fish Conditions Stage Qualifier Anatomy Assay
sparc AB standard conditions 10-13 somites otic placode ISH
Protruding-mouth floor plate ISH
Protruding-mouth Not Detected notochord ISH
Protruding-mouth pronephros ISH
Protruding-mouth ventral fin fold ISH
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
AB + MO2-sparc standard conditions Day 4 ceratobranchial cartilage aplastic, abnormal
Day 4 ceratohyal cartilage decreased size, abnormal
Day 4 chondrocranium cartilage decreased size, abnormal
Day 4 Meckel's cartilage decreased size, abnormal
Day 4 pectoral fin decreased size, abnormal
Day 4 pectoral fin kinked, abnormal
Day 4 ventral mandibular arch decreased size, abnormal
Day 4 vestibuloauditory system functionality, abnormal
Day 4 whole organism decreased length, abnormal
Days 7-13 whole organism lethal (sensu genetics), abnormal
AB + MO3-sparc standard conditions Days 7-13 whole organism lethal (sensu genetics), abnormal
Full text @ Matrix Biol.