ZFIN

ZFIN ID: ZDB-GENE-110524-4

ZFIN ID: ZDB-GENE-110524-4

CITATIONS (57 total)

Gene Name:	thyroid stimulating hormone receptor
Gene Symbol:	tshr

Ka, Y., Lee, I., Ji, K. (2024) Thyroid and growth hormone endocrine disruption and mechanisms of homosalate and octisalate using wild-type, thrαa^-/-, and dre-miR-499^-/- zebrafish embryo/larvae. Ecotoxicology and environmental safety. 286:117170117170

Chopra, K., Folkmanaitė, M., Stockdale, L., Shathish, V., Ishibashi, S., Bergin, R., Amich, J., Amaya, E. (2023) Duox is the primary NADPH oxidase responsible for ROS production during adult caudal fin regeneration in zebrafish. iScience. 26:106147106147

Harper, M., Hu, Y., Donahue, J., Acosta, B., Dievenich Braes, F., Nguyen, S., Zeng, J., Barbaro, J., Lee, H., Bui, H., McMenamin, S.K. (2023) Thyroid hormone regulates proximodistal patterning in fin rays. Proceedings of the National Academy of Sciences of the United States of America. 120:e2219770120e2219770120

Yang, L., Tu, P.H., Zhang, C.X., Xie, R.R., Dong, M., Jing, Y., Chen, X., Wei, G., Song, H.D. (2023) Influence of two anti-tumor drugs, pazopanib, and axitinib, on the development and thyroid-axis of zebrafish (Danio rerio) embryos/larvae. Frontiers in endocrinology. 14:12046781204678

Ding, W., Chen, Y., Sultan, Y., Ma, J., Feng, Y., Li, X. (2022) Effect of Acute Exposure to the Ionic Liquid 1-Methyl-3-octylimidazolium Chloride on the Embryonic Development and Larval Thyroid System of Zebrafish. Animals : an open access journal from MDPI. 12(11)

Keer, S., Storch, J.D., Nguyen, S., Prado, M., Singh, R., Hernandez, L.P., McMenamin, S.K. (2022) Thyroid hormone shapes craniofacial bones during postembryonic zebrafish development. Evolution & development. 24(1-2):61-76

Wang, H., Dong, F., Zhao, Y., Fu, S., Zhao, H., Liu, S., Zhang, W., Hu, F. (2022) Exposure to diclofenac alters thyroid hormone levels and transcription of genes involved in the hypothalamic-pituitary-thyroid axis in zebrafish embryos/larvae. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 257:109335

Chu, S., Kwon, B.R., Lee, Y.M., Zoh, K.D., Choi, K. (2021) Effects of 2-ethylhexyl-4-methoxycinnamate (EHMC) on thyroid hormones and genes associated with thyroid, neurotoxic, and nephrotoxic responses in adult and larval zebrafish (Danio rerio). Chemosphere. 263:128176

Hu, F., Zhao, Y., Yuan, Y., Yin, L., Dong, F., Zhang, W., Chen, X. (2021) Effects of environmentally relevant concentrations of tris (2-chloroethyl) phosphate (TCEP) on early life stages of zebrafish (Danio rerio). Environmental Toxicology and Pharmacology. 83:103600

Jin, M., Dang, J., Paudel, Y.N., Wang, X., Wang, B., Wang, L., Li, P., Sun, C., Liu, K. (2021) The possible hormetic effects of fluorene-9-bisphenol on regulating hypothalamic-pituitary-thyroid axis in zebrafish. The Science of the total environment. 776:145963

Kim, J., Lee, G., Lee, Y.M., Zoh, K.D., Choi, K. (2021) Thyroid disrupting effects of perfluoroundecanoic acid and perfluorotridecanoic acid in zebrafish (Danio rerio) and rat pituitary (GH3) cell line. Chemosphere. 262:128012

Chen, X., Teng, M., Zhang, J., Qian, L., Duan, M., Cheng, Y., Zhao, F., Zheng, J., Wang, C. (2020) Tralopyril induces developmental toxicity in zebrafish embryo (Danio rerio) by disrupting the thyroid system and metabolism. The Science of the total environment. 746:141860

Kim, S., Stroski, K.M., Killeen, G., Smitherman, C., Simcik, M.F., Brooks, B.W. (2020) 8:8 Perfluoroalkyl phosphinic acid affects neurobehavioral development, thyroid disruption, and DNA methylation in developing zebrafish. The Science of the total environment. 736:139600

Lee, S., Eghan, K., Lee, J., Yoo, D., Yoon, S., Kim, W.K. (2020) Zebrafish Embryonic Exposure to BPAP and Its Relatively Weak Thyroid Hormone-Disrupting Effects. Toxics. 8(4):

Zhang, M., Zhao, F., Zhang, J., Shi, J., Tao, H., Ge, H., Guo, W., Liu, D., Cai, Z. (2020) Toxicity and accumulation of 6-OH-BDE-47 and newly synthesized 6,6'-diOH-BDE-47 in early life-stages of Zebrafish (Danio rerio). The Science of the total environment. 763:143036

Galindo, D., Sweet, E., DeLeon, Z., Wagner, M., DeLeon, A., Carter, C., McMenamin, S.K., Cooper, W.J. (2019) Thyroid hormone modulation during zebrafish development recapitulates evolved diversity in danionin jaw protrusion mechanics. Evolution & development. 21(5):231-246

Jiao, F., Qiao, K., Jiang, Y., Li, S., Zhao, J., Gui, W. (2019) Integrated thyroid endocrine disrupting effect on zebrafish (Danio rario) larvae via simultaneously repressing type II iodothyronine deiodinase and activating thyroid receptor-mediated signaling following waterborne exposure to trace azocyclotin. Environmental pollution (Barking, Essex : 1987). 255:113328

Kim, H., Ji, K. (2019) Exposure to humidifier disinfectants induces developmental effects and disrupts thyroid endocrine systems in zebrafish larvae. Ecotoxicology and environmental safety. 184:109663

Lee, S., Kim, C., Shin, H., Kho, Y., Choi, K. (2019) Comparison of thyroid hormone disruption potentials by bisphenols A, S, F, and Z in embryo-larval zebrafish. Chemosphere. 221:115-123

Teng, M., Zhu, W., Wang, D., Yan, J., Qi, S., Song, M., Wang, C. (2018) Acute exposure of zebrafish embryo (Danio rerio) to flutolanil reveals its developmental mechanism of toxicity via disrupting the thyroid system and metabolism. Environmental pollution (Barking, Essex : 1987). 242:1157-1165

Trubiroha, A., Gillotay, P., Giusti, N., Gacquer, D., Libert, F., Lefort, A., Haerlingen, B., De Deken, X., Opitz, R., Costagliola, S. (2018) A Rapid CRISPR/Cas-based Mutagenesis Assay in Zebrafish for Identification of Genes Involved in Thyroid Morphogenesis and Function. Scientific Reports. 8:5647

Vergauwen, L., Cavallin, J.E., Ankley, G.T., Bars, C., Gabriëls, I.J., Michiels, E.D.G., Fitzpatrick, K.R., Periz-Stanacev, J., Randolph, E.C., Robinson, S.L., Saari, T.W., Schroeder, A.L., Stinckens, E., Swintek, J., Van Cruchten, S.J., Verbueken, E., Villeneuve, D.L., Knapen, D. (2018) Gene transcription ontogeny of hypothalamic-pituitary-thyroid axis development in early-life stage fathead minnow and zebrafish. General and comparative endocrinology. 266:87-100

Cheng, H., Yan, W., Wu, Q., Liu, C., Gong, X., Hung, T.C., Li, G. (2017) Parental exposure to microcystin-LR induced thyroid endocrine disruption in zebrafish offspring, a transgenerational toxicity. Environmental pollution (Barking, Essex : 1987). 230:981-988

Dong, X., Xu, H., Wu, X., Yang, L. (2017) Multiple bioanalytical method to reveal developmental biological responses in zebrafish embryos exposed to triclocarban. Chemosphere. 193:251-258

Hur, M., Gistelinck, C.A., Huber, P., Lee, J., Thompson, M.H., Monstad-Rios, A.T., Watson, C.J., McMenamin, S.K., Willaert, A., Parichy, D.M., Coucke, P., Kwon, R.Y. (2017) microCT-based phenomics in the zebrafish skeleton reveals virtues of deep phenotyping in a distributed organ system. eLIFE. 6

Liang, X., Li, J., Martyniuk, C.J., Wang, J., Mao, Y., Lu, H., Zha, J. (2017) Benzotriazole ultraviolet stabilizers alter the expression of the thyroid hormone pathway in zebrafish (Danio rerio) embryos. Chemosphere. 182:22-30

Liu, Y., Wu, D., Xu, Q., Yu, L., Liu, C., Wang, J. (2017) Acute exposure to tris (2-butoxyethyl) phosphate (TBOEP) affects growth and development of embryo-larval zebrafish. Aquatic toxicology (Amsterdam, Netherlands). 191:17-24

Kang, H., Moon, H.B., Choi, K. (2016) Toxicological responses following short-term exposure through gavage feeding or water-borne exposure to Dechlorane Plus in zebrafish (Danio rerio). Chemosphere. 146:226-232

Kim, S., Sohn, J.H., Ha, S.Y., Kang, H., Yim, U.H., Shim, W.J., Khim, J.S., Jung, D., Choi, K. (2016) Thyroid hormone disruption by water-accommodated fractions of crude oil and sediments affected by the Hebei Spirit oil spill in zebrafish and GH3 cells. Environmental science & technology. 50(11):5972-80

Ma, Z., Tang, S., Su, G., Miao, Y., Liu, H., Xie, Y., Giesy, J.P., Saunders, D.M., Hecker, M., Yu, H. (2016) Effects of tris (2-butoxyethyl) phosphate (TBOEP) on endocrine axes during development of early life stages of zebrafish (Danio rerio). Chemosphere. 144:1920-1927

Eom, D.S., Bain, E.J., Patterson, L.B., Grout, M.E., Parichy, D.M. (2015) Long-distance communication by specialized cellular projections during pigment pattern development and evolution. eLIFE. 4

Kim, S., Jung, J., Lee, I., Jung, D., Youn, H., Choi, K. (2015) Thyroid disruption by triphenyl phosphate, an organophosphate flame retardant, in zebrafish (Danio rerio) embryos/larvae, and in GH3 and FRTL-5 cell lines. Aquatic toxicology (Amsterdam, Netherlands). 160C:188-196

Pappalardo, A., Porreca, I., Caputi, L., De Felice, E., Schulte-Merker, S., Zannini, M., Sordino, P. (2015) Thyroid development in zebrafish lacking Taz. Mechanisms of Development. 138 Pt 3:268-78

Maugars, G., Dufour, S., Cohen-Tannoudji, J., Quérat, B. (2014) Multiple Thyrotropin β-Subunit and Thyrotropin Receptor-Related Genes Arose during Vertebrate Evolution. PLoS One. 9:e111361

McMenamin, S.K., Bain, E.J., McCann, A.E., Patterson, L.B., Eom, D.S., Waller, Z.P., Hamill, J.C., Kuhlman, J.A., Eisen, J.S., Parichy, D.M. (2014) Thyroid hormone-dependent adult pigment cell lineage and pattern in zebrafish. Science (New York, N.Y.). 345(6202):1358-61

Liu, C., Yu, H., and Zhang, X. (2013) Zebrafish embryos/larvae for rapid determination of effects on hypothalamic-pituitary-thyroid (HPT) and hypothalamic-pituitary-interrenal (HPI) axis: mRNA expression. Chemosphere. 93(10):2327-32

Zheng, X., Zhu, Y., Liu, C., Liu, H., Giesy, J.P., Hecker, M., Lam, M.H., and Yu, H. (2012) Accumulation and Biotransformation of BDE-47 by Zebrafish Larvae and Teratogenicity and Expression of Genes along the Hypothalamus-Pituitary-Thyroid Axis. Environmental science & technology. 46(23):12943-12951

Liu, C., Zhang, X., Deng, J., Hecker, M., Al-Khedhairy, A., Giesy, J.P., and Zhou, B. (2011) Effects of Prochloraz or Propylthiouracil on the Cross-Talk between the HPG, HPA, and HPT Axes in Zebrafish. Environmental science & technology. 45(2):769-775

McGrail, M., Hatler, J.M., Kuang, X., Liao, H.K., Nannapaneni, K., Noack Watt, K.E., Uhl, J.D., Largaespada, D.A., Vollbrecht, E., Scheetz, T.E., Dupuy, A.J., Hostetter, J.M., and Essner, J.J. (2011) Somatic mutagenesis with a sleeping beauty transposon system leads to solid tumor formation in zebrafish. PLoS One. 6(4):e18826

Opitz, R., Maquet, E., Zoenen, M., Dadhich, R., and Costagliola, S. (2011) TSH Receptor Function Is Required for Normal Thyroid Differentiation in Zebrafish. Molecular endocrinology (Baltimore, Md.). 25(9):1579-99

Additional Citations (17):

ZFIN Staff (2024) Association of Ensembl transcripts with ZFIN genes. Semi-automated Curation.

ZFIN Staff (2023) Automated Curation of UniProt Database Links. Automated Data Submission.

ZFIN Staff (2020) Addition of links from ZFIN to Expression Atlas. Semi-automated Curation.

ZFIN Staff (2017) Curation of PANTHER Gene IDs. Automated Data Submission.

ZFIN Staff (2017) Curation of Alliance of Genome Resources Database Links. Automated Data Submission.

ZFIN Staff (2015) Data Model Change: Sequence Targeting Reagents Removed from Environment. ZFIN Historical Data.

Busch-Nentwich, E., Kettleborough, R., Dooley, C. M., Scahill, C., Sealy, I., White, R., Herd, C., Mehroke, S., Wali, N., Carruthers, S., Hall, A., Collins, J., Gibbons, R., Pusztai, Z., Clark, R., and Stemple, D.L. (2013) Sanger Institute Zebrafish Mutation Project mutant data submission. ZFIN Direct Data Submission.

ZFIN Staff (2013) Semi-automated association of ENSDARG identifiers with ZFIN genes for the ZMP project. Semi-automated Curation.

UniProt-GOA (2011) Gene Ontology annotation based on the automatic assignment of UniProtKB Subcellular Location terms in UniProtKB/TrEMBL entries. Manually curated data.

Gaudet, P., Livstone, M., Thomas, P., The Reference Genome Project (2010) Annotation inferences using phylogenetic trees. Automated Data Submission.

ZFIN Staff (2006) Curation of Ensembl Database Links. Automated Data Submission.

ZFIN Staff (2003) Curation of orthology data. Manually curated data.

ZFIN Staff (2003) Curation of unpublished nucleotide sequence accession numbers. Manually curated data.

ZFIN Staff (2002) Gene Ontology Annotation Through Association of UniProt Keywords with GO Terms. Automated Data Submission.

ZFIN Staff (2002) Curation of NCBI Gene Data Via Shared RNA Sequence IDs. Automated Data Submission.

ZFIN Staff (2002) Scientific Curation. Manually curated data.

ZFIN Staff (2002) Gene Ontology Annotation Through Association of InterPro Records with GO Terms. Automated Data Submission.