ZFIN

ZFIN ID: ZDB-GENE-081104-438

ZFIN ID: ZDB-GENE-081104-438

CITATIONS (53 total)

Gene Name:	interferon induced with helicase C domain 1
Gene Symbol:	ifih1

Li, Z., Li, J., Li, Z., Song, Y., Wang, Y., Wang, C., Yuan, L., Xiao, W., Wang, J. (2024) Zebrafish mylipb attenuates antiviral innate immunity through two synergistic mechanisms targeting transcription factor irf3. PLoS pathogens. 20:e1012227e1012227

Qu, Z.L., Gong, X.Y., An, L.L., Sun, H.Y., Guo, W.H., Luan, H.Y., Wu, M.Y., Dan, C., Gui, J.F., Zhang, Y.B. (2024) Genome editing of FTR42 improves zebrafish survival against virus infection by enhancing IFN immunity. iScience. 27:109497109497

Bernal-Bermúdez, B., Martínez-López, A., Martínez-Morcillo, F.J., Tyrkalska, S.D., Martínez-Menchón, T., Mesa-Del-Castillo, P., Cayuela, M.L., Mulero, V., García-Moreno, D. (2023) A zebrafish model of Ifih1-driven Aicardi-Goutières syndrome reproduces the interferon signature and the exacerbated inflammation of patients. Frontiers in immunology. 14:12947661294766

Wu, J., Li, J., Chen, K., Liu, G., Zhou, Y., Chen, W., Zhu, X., Ni, T.T., Zhang, B., Jin, D., Li, D., Kang, L., Wu, Y., Zhu, P., Xie, P., Zhong, T.P. (2023) Atf7ip and Setdb1 interaction orchestrates the hematopoietic stem and progenitor cell state with diverse lineage differentiation. Proceedings of the National Academy of Sciences of the United States of America. 120:e2209062120e2209062120

Gong, X.Y., Zhang, Q.M., Zhao, X., Li, Y.L., Qu, Z.L., Li, Z., Dan, C., Gui, J.F., Zhang, Y.B. (2022) LGP2 is essential for zebrafish survival through dual regulation of IFN antiviral response. iScience. 25:104821

Huang, W., Zhao, X., Ji, N., Guo, J., Feng, J., Chen, K., Wu, Y., Wang, J., Feng, H., Zou, J. (2022) IRF2 Cooperates with Phosphoprotein of Spring Viremia of Carp Virus to Suppress Antiviral Response in Zebrafish. Journal of virology. 96(22):e0131422

Zhao, X., Dan, C., Gong, X.Y., Li, Y.L., Qu, Z.L., Sun, H.Y., An, L.L., Guo, W.H., Gui, J.F., Zhang, Y.B. (2022) Zebrafish MARCH8 downregulates fish IFN response by targeting MITA and TBK1 for protein degradation. Developmental and comparative immunology. 135:104485

Liao, Q., Ouyang, G., Zhu, J., Cai, X., Yu, G., Zhou, Z., Liu, X., Wang, J., Xiao, W. (2021) Zebrafish sirt7 Negatively Regulates Antiviral Responses by Attenuating Phosphorylation of irf3 and irf7 Independent of Its Enzymatic Activity. Journal of immunology (Baltimore, Md. : 1950). 207(12):3050-3059

Wu, X.M., Fang, H., Zhang, J., Bi, Y.H., Chang, M.X. (2021) Histone H2A Nuclear/Cytoplasmic Trafficking Is Essential for Negative Regulation of Antiviral Immune Response and Lysosomal Degradation of TBK1 and IRF3. Frontiers in immunology. 12:771277

Dong, Z., Li, Y., Chen, X., Lai, X., Liu, M. (2020) A comparative study of the expression patterns of Fign family members in zebrafish embryonic development. Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology. 251:110522

Lefkopoulos, S., Polyzou, A., Derecka, M., Bergo, V., Clapes, T., Cauchy, P., Jerez-Longres, C., Onishi-Seebacher, M., Yin, N., Martagon-Calderón, N.A., Potts, K.S., Klaeylé, L., Liu, F., Bowman, T.V., Jenuwein, T., Mione, M.C., Trompouki, E. (2020) Repetitive Elements Trigger RIG-I-like Receptor Signaling that Regulates the Emergence of Hematopoietic Stem and Progenitor Cells. Immunity. 53:934-951.e9

Liu, R., Hu, X., Lü, A., Song, Y., Lian, Z., Sun, J., Sung, Y.Y. (2020) Proteomic Profiling of Zebrafish Challenged by Spring Viremia of Carp Virus Provides Insight into Skin Antiviral Response. Zebrafish. 17:91-103

Wu, X.M., Zhang, J., Li, P.W., Hu, Y.W., Cao, L., Ouyang, S., Bi, Y.H., Nie, P., Chang, M.X. (2020) NOD1 Promotes Antiviral Signaling by Binding Viral RNA and Regulating the Interaction of MDA5 and MAVS. Journal of immunology (Baltimore, Md. : 1950). 204(8):2216-2231

Xiong, F., Cao, L., Wu, X.M., Chang, M.X. (2020) The function of zebrafish gpbar1 in antiviral response and lipid metabolism. Developmental and comparative immunology. 116:103955

Zhang, J., Wu, X.M., Hu, Y.W., Chang, M.X. (2020) A Novel Transcript Isoform of TBK1 Negatively Regulates Type I IFN Production by Promoting Proteasomal Degradation of TBK1 and Lysosomal Degradation of IRF3. Frontiers in immunology. 11:580864

Zhu, J., Liu, X., Cai, X., Ouyang, G., Fan, S., Wang, J., Xiao, W. (2020) Zebrafish prmt7 negatively regulates antiviral responses by suppressing the retinoic acid-inducible gene-I-like receptor signaling. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 34:988-1000

Liu, G., Wang, C., Wang, H., Zhu, L., Zhang, H., Wang, Y., Pei, C., Liu, L. (2019) Antiviral efficiency of a coumarin derivative on spring viremia of carp virus in vivo. Virus research. 268:11-17

Danilova, N., Wilkes, M., Bibikova, E., Youn, M.Y., Sakamoto, K.M., Lin, S. (2018) Innate immune system activation in zebrafish and cellular models of Diamond Blackfan Anemia. Scientific Reports. 8:5165

Irwin, D.M., Mojsov, S. (2018) Diversification of the functions of proglucagon and glucagon receptor genes in fish. General and comparative endocrinology. 261:148-165

Lai, Y., Liang, M., Hu, ., Zeng, Z., Lin, H., Yi, G., Li, M., Liu, Z. (2018) RNF135 is a positive regulator of IFN expression and involved in RIG-I signaling pathway by targeting RIG-I. Fish & shellfish immunology. 86:474-479

Rajshekar, S., Yao, J., Arnold, P.K., Payne, S.G., Zhang, Y., Bowman, T.V., Schmitz, R.J., Edwards, J.R., Goll, M. (2018) Pericentromeric hypomethylation elicits an interferon response in an animal model of ICF syndrome. eLIFE. 7:

Liu, J., Li, J., Xiao, J., Chen, H., Lu, L., Wang, X., Tian, Y., Feng, H. (2017) The antiviral signaling mediated by black carp MDA5 is positively regulated by LGP2. Fish & shellfish immunology. 66:360-371

Zhang, Q.M., Zhao, X., Li, Z., Wu, M., Gui, J.F., Zhang, Y.B. (2017) Alternative Splicing Transcripts of Zebrafish LGP2 Gene Differentially Contribute to IFN Antiviral Response. Journal of immunology (Baltimore, Md. : 1950). 200(2):688-703

Kavaliauskis, A., Arnemo, M., Speth, M.T., Lagos, L., Rishovd, A.L., Estepa, A., Griffiths, G., Gjøen, T. (2016) Protective effect of a recombinant VHSV-G vaccine using poly(I:C) loaded nanoparticles as an adjuvant in zebrafish (Danio rerio) infection model. Developmental and comparative immunology. 61:248-57

Zou, P.F., Chang, M.X., Li, Y., Xue, N.N., Li, J.H., Chen, S.N., Nie, P. (2016) NOD2 in zebrafish functions in antibacterial and also antiviral responses via NF-κB, and also MDA5, RIG-I and MAVS. Fish & shellfish immunology. 55:173-85

Chen, H.Y., Liu, W., Wu, S.Y., Chiou, P.P., Li, Y.H., Chen, Y.C., Lin, G.H., Lu, M.W., Wu, J.L. (2015) RIG-I specifically mediates group II type I IFN activation in nervous necrosis virus infected zebrafish cells. Fish & shellfish immunology. 43(2):427-35

Chen, W.Q., Hu, Y.W., Zou, P.F., Ren, S.S., Nie, P., Chang, M.X. (2015) MAVS splicing variants contribute to the induction of interferon and interferon-stimulated genes mediated by RIG-I-like receptors. Developmental and comparative immunology. 49:19-30

Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549

Estepa, A., Coll, J. (2015) Innate Multigene Family Memories Are Implicated in the Viral-Survivor Zebrafish Phenotype. PLoS One. 10:e0135483

Gabor, K., Charette, J., Pietraszewski, M., Wingfield, D., Shim, J., Millard, P., Kim, C. (2015) A DN-mda5 transgenic zebrafish model demonstrates that Mda5 plays an important role in snakehead rhabdovirus resistance. Developmental and comparative immunology. 51(2):298-304

Kavaliauskis, A., Arnemo, M., Kim, S.H., Ulanova, L., Speth, M., Novoa, B., Dios, S., Evensen, Ø., Griffiths, G.W., Gjøen, T. (2015) Use of Poly(I:C) Stabilized with Chitosan As a Vaccine-Adjuvant Against Viral Hemorrhagic Septicemia Virus Infection in Zebrafish. Zebrafish. 12(6):421-31

Nie, L., Zhang, Y.S., Dong, W.R., Xiang, L.X., Shao, J.Z. (2015) Involvement of zebrafish RIG-I in NF-κB and IFN signaling pathways: Insights into functional conservation of RIG-I in antiviral innate immunity. Developmental and comparative immunology. 48(1):95-101

Wang, W., Asim, M., Yi, L., Hegazy, A.M., Hu, X., Zhou, Y., Ai, T., Lin, L. (2015) Abortive Infection of Snakehead Fish Vesiculovirus in ZF4 Cells Was Associated with the RLRs Pathway Activation by Viral Replicative Intermediates. International Journal of Molecular Sciences. 16:6235-50

Briolat, V., Jouneau, L., Carvalho, R., Palha, N., Langevin, C., Herbomel, P., Schwartz, O., Spaink, H.P., Levraud, J.P., Boudinot, P. (2014) Contrasted Innate Responses to Two Viruses in Zebrafish: Insights into the Ancestral Repertoire of Vertebrate IFN-Stimulated Genes. Journal of immunology (Baltimore, Md. : 1950). 192:4328-41

Varela, M., Romero, A., Dios, S., van der Vaart, M., Figueras, A., Meijer, A.H., Novoa, B. (2014) Cellular Visualization of Macrophage Pyroptosis and Interleukin-1β Release in a Viral Hemorrhagic Infection in Zebrafish Larvae. Journal of virology. 88(20):12026-40

Zou, P.F., Chang, M.X., Xue, N.N., Liu, X.Q., Li, J.H., Fu, J.P., Chen, S.N., and Nie, P. (2014) Melanoma differentiation-associated gene 5 in zebrafish provoking higher interferon-promoter activity through signalling enhancing of its shorter splicing variant. Immunology. 141(2):192-202

Dios, S., Romero, A., Chamorro, R., Figueras, A., and Novoa, B. (2010) Effect Of The Temperature During Antiviral Immune Response Ontogeny In Teleosts. Fish & shellfish immunology. 29(6):1019-1027

Biacchesi, S., Leberre, M., Lamoureux, A., Louise, Y., Lauret, E., Boudinot, P., and Brémont, M. (2009) Mitochondrial Antiviral Signaling Protein Plays a Major Role in Induction of the Fish Innate Immune Response against RNA and DNA Viruses. Journal of virology. 83(16):7815-7827

Additional Citations (15):

ZFIN Staff (2024) Association of Ensembl transcripts with ZFIN genes. Semi-automated Curation.

ZFIN Staff (2023) Automated Curation of UniProt Database Links. Automated Data Submission.

ZFIN Staff (2020) Addition of links from ZFIN to Expression Atlas. Semi-automated Curation.

ZFIN Staff (2017) Curation of PANTHER Gene IDs. Automated Data Submission.

ZFIN Staff (2017) Curation of Alliance of Genome Resources Database Links. Automated Data Submission.

Busch-Nentwich, E., Kettleborough, R., Dooley, C. M., Scahill, C., Sealy, I., White, R., Herd, C., Mehroke, S., Wali, N., Carruthers, S., Hall, A., Collins, J., Gibbons, R., Pusztai, Z., Clark, R., and Stemple, D.L. (2013) Sanger Institute Zebrafish Mutation Project mutant data submission. ZFIN Direct Data Submission.

ZFIN Staff (2013) Semi-automated association of ENSDARG identifiers with ZFIN genes for the ZMP project. Semi-automated Curation.

Gaudet, P., Livstone, M., Thomas, P., The Reference Genome Project (2010) Annotation inferences using phylogenetic trees. Automated Data Submission.

ZFIN Staff (2006) Curation of Ensembl Database Links. Automated Data Submission.

ZFIN Staff (2003) Curation of VEGA Database Links. Automated Data Submission.

ZFIN Staff (2003) Curation of orthology data. Manually curated data.

ZFIN Staff (2003) Gene Ontology Annotation Through Association of Enzyme Commission numbers with GO Terms. Automated Data Submission.

ZFIN Staff (2002) Gene Ontology Annotation Through Association of UniProt Keywords with GO Terms. Automated Data Submission.

ZFIN Staff (2002) Curation of NCBI Gene Data Via Shared RNA Sequence IDs. Automated Data Submission.

ZFIN Staff (2002) Gene Ontology Annotation Through Association of InterPro Records with GO Terms. Automated Data Submission.