ZFIN

ZFIN ID: ZDB-GENE-050105-2

ZFIN ID: ZDB-GENE-050105-2

CITATIONS (63 total)

Gene Name:	solute carrier family 6 member 5
Gene Symbol:	slc6a5

Guo, J., Zou, Z., Dou, X., Zhao, X., Wang, Y., Wei, L., Pi, Y., Wang, Y., He, C., Guo, S. (2024) Zebrafish Mbd5 binds to RNA m5C and regulates histone deubiquitylation and gene expression in development metabolism and behavior. Nucleic acids research. 52(8):4257-4275

England, S.J., Rusnock, A.K., Mujcic, A., Kowalchuk, A., de Jager, S., Hilinski, W.C., Juárez-Morales, J.L., Smith, M.E., Grieb, G., Banerjee, S., Lewis, K.E. (2023) Molecular analyses of zebrafish V0v spinal interneurons and identification of transcriptional regulators downstream of Evx1 and Evx2 in these cells. Neural Development. 18:88

Chen, Z., Long, H., Guo, J., Wang, Y., He, K., Tao, C., Li, X., Jiang, K., Guo, S., Pi, Y. (2022) Autism-Risk Gene necab2 Regulates Psychomotor and Social Behavior as a Neuronal Modulator of mGluR1 Signaling. Frontiers in molecular neuroscience. 15:901682

Hevia, C.F., Engel-Pizcueta, C., Udina, F., Pujades, C. (2022) The neurogenic fate of the hindbrain boundaries relies on Notch3-dependent asymmetric cell divisions. Cell Reports. 39:110915

Long, F., Zheng, J., Zhou, J., Hu, P., Xiong, B. (2022) Knockout of tanc2 causes autism-like behavior and sleep disturbance in zebrafish. Autism research : official journal of the International Society for Autism Research. 16(3):524-534

Rajan, G., Lafaye, J., Faini, G., Carbo-Tano, M., Duroure, K., Tanese, D., Panier, T., Candelier, R., Henninger, J., Britz, R., Judkewitz, B., Gebhardt, C., Emiliani, V., Debregeas, G., Wyart, C., Del Bene, F. (2022) Evolutionary divergence of locomotion in two related vertebrate species. Cell Reports. 38:110585

de la Rocha-Muñoz, A., Núñez, E., Vishwanath, A.A., Gómez-López, S., Dhanasobhon, D., Rebola, N., López-Corcuera, B., de Juan-Sanz, J., Aragón, C. (2021) The presynaptic glycine transporter GlyT2 is regulated by the Hedgehog pathway in vitro and in vivo. Communications biology. 4:1197

Juárez-Morales, J.L., Weierud, F., England, S.J., Demby, C., Santos, N., Grieb, G., Mazan, S., Lewis, K.E. (2021) Evolution of lbx spinal cord expression and function. Evolution & development. 23(5):404-422

Picton, L.D., Bertuzzi, M., Pallucchi, I., Fontanel, P., Dahlberg, E., Björnfors, E.R., Iacoviello, F., Shearing, P.R., El Manira, A. (2021) A spinal organ of proprioception for integrated motor action feedback. Neuron. 109(7):1188-1201.e7

Wang, T., Zhou, M., Zhang, Q., Zhang, C., Peng, G. (2021) ubtor Mutation Causes Motor Hyperactivity by Activating mTOR Signaling in Zebrafish. Neuroscience Bulletin. 37(12):1658-1670

England, S.J., Cerda, G.A., Kowalchuk, A., Sorice, T., Grieb, G., Lewis, K.E. (2020) Hmx3a Has Essential Functions in Zebrafish Spinal Cord, Ear and Lateral Line Development. Genetics. 216(4):1153-1185

Satou, C., Sugioka, T., Uemura, Y., Shimazaki, T., Zmarz, P., Kimura, Y., Higashijima, S.I. (2020) Functional Diversity of Glycinergic Commissural Inhibitory Neurons in Larval Zebrafish. Cell Reports. 30:3036-3050.e4

Callahan, R.A., Roberts, R., Sengupta, M., Kimura, Y., Higashijima, S.I., Bagnall, M.W. (2019) Spinal V2b neurons reveal a role for ipsilateral inhibition in speed control. eLIFE. 8:

Gerber, V., Yang, L., Takamiya, M., Ribes, V., Gourain, V., Peravali, R., Stegmaier, J., Mikut, R., Reischl, M., Ferg, M., Rastegar, S., Strähle, U. (2019) The HMG box transcription factors Sox1a and b specify a new class of glycinergic interneurons in the spinal cord of zebrafish embryos. Development (Cambridge, England). 146(4):

Liu, H., Liu, Z.Z. (2019) Aggressive-like behavior and increased glycine transporters in a zebrafish model of CHARGE syndrome. Behavioural brain research. 378:112293

Bayés, À., Collins, M.O., Reig-Viader, R., Gou, G., Goulding, D., Izquierdo, A., Choudhary, J.S., Emes, R.D., Grant, S.G. (2017) Evolution of complexity in the zebrafish synapse proteome. Nature communications. 8:14613

Hilinski, W.C., Bostrom, J.R., England, S.J., Juárez-Morales, J.L., de Jager, S., Armant, O., Legradi, J., Strähle, U., Link, B.A., Lewis, K.E. (2016) Lmx1b is required for the glutamatergic fates of a subset of spinal cord neurons. Neural Development. 11:16

Hoffman, E.J., Turner, K.J., Fernandez, J.M., Cifuentes, D., Ghosh, M., Ijaz, S., Jain, R.A., Kubo, F., Bill, B.R., Baier, H., Granato, M., Barresi, M.J., Wilson, S.W., Rihel, J., State, M.W., Giraldez, A.J. (2016) Estrogens Suppress a Behavioral Phenotype in Zebrafish Mutants of the Autism Risk Gene, CNTNAP2. Neuron. 89(4):725-33

Juárez-Morales, J.L., Schulte, C.J., Pezoa, S.A., Vallejo, G.K., Hilinski, W.C., England, S.J., de Jager, S., Lewis, K.E. (2016) Evx1 and Evx2 specify excitatory neurotransmitter fates and suppress inhibitory fates through a Pax2-independent mechanism. Neural Development. 11:5

May, M., Hwang, K.S., Miles, J., Williams, C., Niranjan, T., Kahler, S.G., Chiurazzi, P., Steindl, K., van der Spek, P.J., Swagemakers, S., Mueller, J., Stefl, S., Alexov, E., Ryu, J.I., Choi, J.H., Kim, H.T., Tarpey, P., Neri, G., Holloway, L., Skinner, C., Stevenson, R.E., Dorsky, R.I., Wang, T., Schwartz, C.E., Kim, C.H. (2015) ZC4H2, an XLID Gene, is Required for the Generation of a Specific Subset of CNS Interneurons. Human molecular genetics. 24(17):4848-61

Kimura, Y., Hisano, Y., Kawahara, A., Higashijima, S. (2014) Efficient generation of knock-in transgenic zebrafish carrying reporter/driver genes by CRISPR/Cas9-mediated genome engineering. Scientific Reports. 4:6545

Moly, P.K., Ikenaga, T., Kamihagi, C., Tariqul Islam, A.F., and Hatta, K. (2014) Identification of initially appearing glycine-immunoreactive neurons in the embryonic zebrafish brain. Developmental Neurobiology. 74(6):616-32

Van Ryswyk, L., Simonson, L., and Eisen, J.S. (2014) The role of inab in axon morphology of an identified zebrafish motoneuron. PLoS One. 9(2):e88631

Barreiro-Iglesias, A., Mysiak, K.S., Adrio, F., Rodicio, M.C., Becker, C.G., Becker, T., and Anadón, R. (2013) Distribution of glycinergic neurons in the brain of glycine transporter-2 Tg(glyt2:gfp) transgenic adult zebrafish: Relation with brain-spinal descending systems. The Journal of comparative neurology. 521(2):389-425

de Juan-Sanz, J., Núñez, E., Villarejo-López, L., Pérez-Hernández, D., Rodriguez-Fraticelli, A.E., López-Corcuera, B., Vázquez, J., and Aragón, C. (2013) Na+/K+-ATPase Is a New Interacting Partner for the Neuronal Glycine Transporter GlyT2 That Downregulates Its Expression In Vitro and In Vivo. The Journal of neuroscience : the official journal of the Society for Neuroscience. 33(35):14269-14281

Fernandes, A.M., Beddows, E., Filippi, A., and Driever, W. (2013) Orthopedia Transcription Factor otpa and otpb Paralogous Genes Function during Dopaminergic and Neuroendocrine Cell Specification in Larval Zebrafish. PLoS One. 8(9):e75002

Ganser, L.R., Yan, Q., James, V.M., Kozol, R., Topf, M., Harvey, R.J., and Dallman, J.E. (2013) Distinct phenotypes in zebrafish models of human startle disease. Neurobiology of disease. 60:139-51

Hirata, H., Ogino, K., Yamada, K., Leacock, S., and Harvey, R.J. (2013) Defective Escape Behavior in DEAH-Box RNA Helicase Mutants Improved by Restoring Glycine Receptor Expression. The Journal of neuroscience : the official journal of the Society for Neuroscience. 33(37):14638-14644

McGown, A., McDearmid, J.R., Panagiotaki, N., Tong, H., Al Mashhadi, S., Redhead, N., Lyon, A.N., Beattie, C.E., Shaw, P.J., and Ramesh, T.M. (2013) Early interneuron dysfunction in ALS: Insights from a mutant sod1 zebrafish model. Annals of neurology. 73(2):246-258

Satou, C., Kimura, Y., Hirata, H., Suster, M.L., Kawakami, K., and Higashijima, S. (2013) Transgenic tools to characterize neuronal properties of discrete populations of zebrafish neurons. Development (Cambridge, England). 140(18):3927-3931

Ronneberger, O., Liu, K., Rath, M., Rueβ, D., Mueller, T., Skibbe, H., Drayer, B., Schmidt, T., Filippi, A., Nitschke, R., Brox, T., Burkhardt, H., Driever, W. (2012) ViBE-Z: a framework for 3D virtual colocalization analysis in zebrafish larval brains. Nature Methods. 9(7):735-742

Roy, N.M., Arpie, B., Lugo, J., Linney, E., Levin, E.D., and Cerutti, D. (2012) Brief embryonic strychnine exposure in zebrafish causes long-term adult behavioral impairment with indications of embryonic synaptic changes. Neurotoxicology and teratology. 34(6):587-591

Satou, C., Kimura, Y., and Higashijima, S. (2012) Generation of multiple classes of v0 neurons in zebrafish spinal cord: progenitor heterogeneity and temporal control of neuronal diversity. The Journal of neuroscience : the official journal of the Society for Neuroscience. 32(5):1771-1783

Seredick, S., Van Ryswyk, L., Hutchinson, S.A., and Eisen, J.S. (2012) Zebrafish Mnx proteins specify one motoneuron subtype and suppress acquisition of interneuron characteristics. Neural Development. 7(1):35

Satou, C., Kimura, Y., Kohashi, T., Horikawa, K., Takeda, H., Oda, Y., and Higashijima, S. (2009) Functional role of a specialized class of spinal commissural inhibitory neurons during fast escapes in zebrafish. The Journal of neuroscience : the official journal of the Society for Neuroscience. 29(21):6780-6793

Webb, K.J., Norton, W.H.J., Trumbach, D., Meijer, A.H., Ninkovic, J., Topp, S., Heck, D., Marr, C., Wurst, W., Theis, F.J., Spaink, H.P., and Bally-Cuif, L. (2009) Zebrafish reward mutants reveal novel transcripts mediating the behavioral effects of amphetamine. Genome biology. 10(7):R81

Batista, M.F., and Lewis, K.E. (2008) Pax2/8 act redundantly to specify glycinergic and GABAergic fates of multiple spinal interneurons. Developmental Biology. 323(1):88-97

Batista, M.F., Jacobstein, J., and Lewis, K.E. (2008) Zebrafish V2 cells develop into excitatory CiD and Notch signalling dependent inhibitory VeLD interneurons. Developmental Biology. 322(2):263-275

Desai, S., Heffelfinger, A.K., Orcutt, T.M., Litman, G.W., and Yoder, J.A. (2008) The medaka novel immune-type receptor (NITR) gene clusters reveal an extraordinary degree of divergence in variable domains. BMC Evolutionary Biology. 8:177

Mongeon, R., Gleason, M.R., Masino, M.A., Fetcho, J.R., Mandel, G., Brehm, P., and Dallman, J.E. (2008) Synaptic homeostasis in a zebrafish glial glycine transporter mutant. Journal of neurophysiology. 100(4):1716-1723

McLean, D.L., Fan, J., Higashijima, S., Hale, M.E., and Fetcho, J.R. (2007) A topographic map of recruitment in spinal cord. Nature. 446(7131):71-75

Yokogawa, T., Marin, W., Faraco, J., Pézeron, G., Appelbaum, L., Zhang, J., Rosa, F., Mourrain, P., and Mignot, E. (2007) Characterization of Sleep in Zebrafish and Insomnia in Hypocretin Receptor Mutants. PLoS Biology. 5(10):2379-2397

Cui, W.W., Low, S.E., Hirata, H., Saint-Amant, L., Geisler, R., Hume, R.I., and Kuwada, J.Y. (2005) The zebrafish shocked gene encodes a glycine transporter and is essential for the function of early neural circuits in the CNS. The Journal of neuroscience : the official journal of the Society for Neuroscience. 25(28):6610-6620

Higashijima, S.I., Mandel, G., and Fetcho, J.R. (2004) Distribution of prospective glutamatergic, glycinergic, and GABAergic neurons in embryonic and larval zebrafish. The Journal of comparative neurology. 480(1):1-18

Higashijima, S.I., Schaefer, M., and Fetcho, J.R. (2004) Neurotransmitter properties of spinal interneurons in embryonic and larval zebrafish. The Journal of comparative neurology. 480(1):19-37

Lo, J., Lee, S., Xu, M., Liu, F., Ruan, H., Eun, A., He, Y., Ma, W., Wang, W., Wen, Z., and Peng, J. (2003) 15,000 unique zebrafish EST clusters and their future use in microarray for profiling gene expression patterns during embryogenesis. Genome research. 13(3):455-466

Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J., and Marra,M.A. (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proceedings of the National Academy of Sciences of the United States of America. 99(26):16899-903

Additional Citations (16):

ZFIN Staff (2024) Association of Ensembl transcripts with ZFIN genes. Semi-automated Curation.

ZFIN Staff (2023) Automated Curation of UniProt Database Links. Automated Data Submission.

ZFIN Staff (2020) Addition of links from ZFIN to Expression Atlas. Semi-automated Curation.

ZFIN Staff (2017) Curation of PANTHER Gene IDs. Automated Data Submission.

ZFIN Staff (2017) Curation of Alliance of Genome Resources Database Links. Automated Data Submission.

ZFIN Staff (2013) Semi-automated association of ENSDARG identifiers with ZFIN genes for the ZMP project. Semi-automated Curation.

UniProt-GOA (2011) Gene Ontology annotation based on the automatic assignment of UniProtKB Subcellular Location terms in UniProtKB/TrEMBL entries. Manually curated data.

Gaudet, P., Livstone, M., Thomas, P., The Reference Genome Project (2010) Annotation inferences using phylogenetic trees. Automated Data Submission.

ZFIN Staff (2006) Curation of Ensembl Database Links. Automated Data Submission.

ZFIN Staff (2004) ZGC Data Curation and Association in ZFIN by ZFIN Staff. Semi-automated Curation.

ZFIN Staff (2003) Curation of VEGA Database Links. Automated Data Submission.

ZFIN Staff (2003) Curation of orthology data. Manually curated data.

ZFIN Staff (2002) Gene Ontology Annotation Through Association of UniProt Keywords with GO Terms. Automated Data Submission.

ZFIN Staff (2002) Curation of NCBI Gene Data Via Shared RNA Sequence IDs. Automated Data Submission.

ZFIN Staff (2002) Gene Ontology Annotation Through Association of InterPro Records with GO Terms. Automated Data Submission.

ZFIN Staff (2002) Curation of EMBL records. Automated Data Submission.