Gene

slc6a5

ID
ZDB-GENE-050105-2
Name
solute carrier family 6 member 5
Symbol
slc6a5 Nomenclature History
Previous Names
  • glyt2 (2)
  • si:dkey-7n10.12
Type
protein_coding_gene
Location
Chr: 7 Mapping Details/Browsers
Description
Predicted to enable glycine:sodium symporter activity. Predicted to be involved in glycine import across plasma membrane; glycinergic synaptic transmission; and sodium ion transmembrane transport. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be integral component of plasma membrane. Is expressed in central nervous system and glycinergic neurons. Human ortholog(s) of this gene implicated in hyperekplexia 3. Orthologous to human SLC6A5 (solute carrier family 6 member 5).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
22 figures from 14 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With slc6a5 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
hyperekplexia 3 Alliance Hyperekplexia 3 614618
Associated With slc6a5 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR000175 Sodium:neurotransmitter symporter
Homologous_superfamily IPR037272 Sodium:neurotransmitter symporter superfamily
Domain Details Per Protein
Protein Length Sodium:neurotransmitter symporter Sodium:neurotransmitter symporter superfamily
UniProtKB:A0A2R8Q8E9 778
UniProtKB:Q5W8I5 786
UniProtKB:Q5SNP7 141
UniProtKB:A0A2R8QPW7 786
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations