ZFIN ID: ZDB-GENE-030131-8064
CITATIONS (62 total)
Gene Name: NFKB activating protein
Gene Symbol: nkap
Le Mentec, H., Monniez, E., Legrand, A., Monvoisin, C., Lagadic-Gossmann, D., Podechard, N. (2023) A New In Vivo Zebrafish Bioassay Evaluating Liver Steatosis Identifies DDE as a Steatogenic Endocrine Disruptor, Partly through SCD1 Regulation. International Journal of Molecular Sciences. 24(4):
Mi, X., Song, Y., Deng, C., Yan, J., Li, Z., Li, Y., Zheng, J., Yang, W., Gong, L., Shi, J. (2023) Stimulation of liver fibrosis by N2 neutrophils in Wilson's disease. Cellular and molecular gastroenterology and hepatology. 16(5):657-684
Wang, Y., Bo, J., Zhao, Z., Han, Y., Zhang, Q., Liu, L. (2023) Depletion of Igfbp7 alleviates zebrafish NAFLD progression through inhibiting hepatic ferroptosis. Life sciences. 332:122086
Chen, J., Tchivelekete, G.M., Zhou, X., Tang, W., Liu, F., Liu, M., Zhao, C., Shu, X., Zeng, Z. (2021) Anti-inflammatory activities of Gardenia jasminoides extracts in retinal pigment epithelial cells and zebrafish embryos. Experimental and Therapeutic Medicine. 22:700
Sireswar, S., Dey, G., Biswas, S. (2021) Influence of fruit-based beverages on efficacy of Lacticaseibacillus rhamnosus GG (Lactobacillus rhamnosus GG) against DSS-induced intestinal inflammation. Food research international (Ottawa, Ont.). 149:110661
Hang, N.T., Nachtergael, A., Mai, N.T., Cornet, V., Duez, P., Muller, M., Ly Huong, D.T., Kestemont, P. (2020) Anti-inflammatory properties of the ethanol extract from Clerodendrum cyrtophyllum Turcz based on in vitro and in vivo studies. Journal of ethnopharmacology. 254:112739
Mawed, S.A., He, Y., Zhang, J., Mei, J. (2020) Strategy of Hepatic Metabolic Defects Induced by beclin1 Heterozygosity in Adult Zebrafish. International Journal of Molecular Sciences. 21(4):
Mi, X., Li, Z., Yan, J., Li, Y., Zheng, J., Zhaung, Z., Yang, W., Gong, L., Shi, J. (2020) Activation of HIF-1 signaling ameliorates liver steatosis in zebrafish atp7b deficiency (Wilson's disease) models. Biochimica et biophysica acta. Molecular basis of disease. 1866(10):165842
Nguyen, T.H., Le, H.D., Kim, T.N.T., The, H.P., Nguyen, T.M., Cornet, V., Lambert, J., Kestemont, P. (2020) Anti-Inflammatory and Antioxidant Properties of the Ethanol Extract of Clerodendrum Cyrtophyllum Turcz in Copper Sulfate-Induced Inflammation in Zebrafish. Antioxidants (Basel, Switzerland). 9(3):
Qin, J., Ru, S., Wang, W., Hao, L., Ru, Y., Wang, J., Zhang, X. (2020) Long-term bisphenol S exposure aggravates non-alcoholic fatty liver by regulating lipid metabolism and inducing endoplasmic reticulum stress response with activation of unfolded protein response in male zebrafish. Environmental pollution (Barking, Essex : 1987). 263:114535
Sun, L., Ling, Y., Jiang, J., Wang, D., Wang, J., Li, J., Wang, X., Wang, H. (2020) Differential mechanisms regarding triclosan vs. bisphenol A and fluorene-9-bisphenol induced zebrafish lipid-metabolism disorders by RNA-Seq. Chemosphere. 251:126318
Yang, H., Lai, H., Huang, J., Sun, L., Mennigen, J.A., Wang, Q., Liu, Y., Jin, Y., Tu, W. (2020) Polystyrene microplastics decrease F-53B bioaccumulation but induce inflammatory stress in larval zebrafish. Chemosphere. 255:127040
Yurtsever, İ., Üstündağ, Ü.V., Ünal, İ., Ateş, P.S., Emekli-Alturfan, E. (2020) Rifampicin decreases neuroinflammation to maintain mitochondrial function and calcium homeostasis in rotenone-treated zebrafish. Drug and chemical toxicology. 45(4):1544-1551
Aksakal, F.I., Ciltas, A. (2019) Impact of copper oxide nanoparticles (CuO NPs) exposure on embryo development and expression of genes related to the innate immune system of zebrafish (Danio rerio). Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 223:78-87
Fiordaliso, S.K., Iwata-Otsubo, A., Ritter, A.L., Quesnel-Vallières, M., Fujiki, K., Nishi, E., Hancarova, M., Miyake, N., Morton, J.E.V., Lee, S., Hackmann, K., Bando, M., Masuda, K., Nakato, R., Arakawa, M., Bhoj, E., Li, D., Hakonarson, H., Takeda, R., Harr, M., Keena, B., Zackai, E.H., Okamoto, N., Mizuno, S., Ko, J.M., Valachova, A., Prchalova, D., Vlckova, M., Pippucci, T., Seiler, C., Choi, M., Matsumoto, N., Di Donato, N., Barash, Y., Sedlacek, Z., Shirahige, K., Izumi, K. (2019) Missense Mutations in NKAP Cause a Disorder of Transcriptional Regulation Characterized by Marfanoid Habitus and Cognitive Impairment. American journal of human genetics. 105(5):987-995
Icoglu Aksakal, F., Ciltas, A., Simsek Ozek, N. (2019) A holistic study on potential toxic effects of carboxylated multi-walled carbon nanotubes (MWCNTs-COOH) on zebrafish (Danio rerio) embryos/larvae. Chemosphere. 225:820-828
Sun, S.X., Zhang, Y.N., Lu, D.L., Wang, W.L., Limbu, S.M., Chen, L.Q., Zhang, M.L., Du, Z.Y. (2019) Concentration-dependent effects of 17β-estradiol and bisphenol A on lipid deposition, inflammation and antioxidant response in male zebrafish (Danio rerio). Chemosphere. 237:124422
Vaishnu Devi, D., Viswanathan, P. (2019) Sulphated polysaccharide from Sargassum myriocystum confers protection against gentamicin-induced nephrotoxicity in adult zebrafish. Environmental Toxicology and Pharmacology. 72:103269
Arias-Jayo, N., Abecia, L., Alonso-Sáez, L., Ramirez-Garcia, A., Rodriguez, A., Pardo, M.A. (2018) High-Fat Diet Consumption Induces Microbiota Dysbiosis and Intestinal Inflammation in Zebrafish. Microbial ecology. 76(4):1089-1101
Lai, C.Y., Lin, C.Y., Hsu, C.C., Yeh, K.Y., Her, G.M. (2018) Liver-directed microRNA-7a depletion induces nonalcoholic fatty liver disease by stabilizing YY1-mediated lipogenic pathways in zebrafish. Biochimica et biophysica acta. 1863(8):844-856
Pérez-Ramos, A., Mohedano, M.L., Pardo, M.Á., López, P. (2018) β-Glucan-Producing Pediococcus parvulus 2.6: Test of Probiotic and Immunomodulatory Properties in Zebrafish Models.. Frontiers in microbiology. 9:1684
Su, B.C., Lai, Y.W., Chen, J.Y., Pan, C.Y. (2018) Transgenic expression of tilapia piscidin 3 (TP3) in zebrafish confers resistance to Streptococcus agalactiae. Fish & shellfish immunology. 74:235-241
Zang, L., Ma, Y., Huang, W., Ling, Y., Sun, L., Wang, X., Zeng, A., Dahlgren, R.A., Wang, C., Wang, H. (2018) Dietary Lactobacillus plantarum ST-III alleviates the toxic effects of triclosan on zebrafish (Danio rerio) via gut microbiota modulation. Fish & shellfish immunology. 84:1157-1169
Hsu, C.C., Lai, C.Y., Lin, C.Y., Yeh, K.Y., Her, G.M. (2017) MicroRNA-27b Depletion Enhances Endotrophic and Intravascular Lipid Accumulation and Induces Adipocyte Hyperplasia in Zebrafish. International Journal of Molecular Sciences. 19(1)
Hu, Z., Wu, B., Meng, F., Zhou, Z., Lu, H., Zhao, H. (2017) Impact of molecular hydrogen treatments on the innate immune activity and survival of zebrafish (Danio rerio) challenged with Aeromonas hydrophila. Fish & shellfish immunology. 67:554-560
Qiu, W., Shao, H., Lei, P., Zheng, C., Qiu, C., Yang, M., Zheng, Y. (2017) Immunotoxicity of bisphenol S and F are similar to that of bisphenol A during zebrafish early development. Chemosphere. 194:1-8
Krishnaraj, C., Harper, S.L., Yun, S.I. (2016) In Vivo toxicological assessment of biologically synthesized silver nanoparticles in adult Zebrafish (Danio rerio). Journal of hazardous materials. 301:480-491
Deng, C., Chen, H., Yang, N., Feng, Y., Hsueh, A.J. (2015) Apela regulates fluid homeostasis by binding to the APJ receptor to activate Gi signaling. The Journal of biological chemistry. 290(30):18261-8
Oyarbide, U., Iturria, I., Rainieri, S., Pardo, M.A. (2015) Use of Gnotobiotic Zebrafish to Study Vibrio anguillarum Pathogenicity. Zebrafish. 12(1):71-80
Zheng, X., Dai, W., Chen, X., Wang, K., Zhang, W., Liu, L., Hou, J. (2015) Caffeine reduces hepatic lipid accumulation through regulation of lipogenesis and ER stress in zebrafish larvae. Journal of Biomedical Science. 22:105
Sreenivasan, R., Jiang, J., Wang, X., Bartfai, R., Kwan, H.Y., Christoffels, A., and Orban, L. (2014) Gonad Differentiation in Zebrafish Is Regulated by the Canonical Wnt Signaling Pathway. Biology of reproduction. 90(2):45
Wang, Y.D., Peng, K.C., Wu, J.L., Chen, J.Y. (2014) Transgenic expression of salmon delta-5 and delta-6 desaturase in zebrafish muscle inhibits the growth of Vibrio alginolyticus and affects fish immunomodulatory activity. Fish & shellfish immunology. 39(2):223-30
Pan, C.Y., Huang, T.C., Wang, Y.D., Yeh, Y.C., Hui, C.F., and Chen, J.Y. (2012) Oral administration of recombinant epinecidin-1 protected grouper (Epinephelus coioides) and zebrafish (Danio rerio) from Vibrio vulnificus infection and enhanced immune-related gene expressions. Fish & shellfish immunology. 32(6):947-957
Pan, C.Y., Peng, K.C., Lin, C.H., and Chen, J.Y. (2011) Transgenic expression of tilapia hepcidin 1-5 and shrimp chelonianin in zebrafish and their resistance to bacterial pathogens. Fish & shellfish immunology. 31(2):275-85
Hsieh, J.C., Pan, C.Y., and Chen, J.Y. (2010) Tilapia hepcidin (TH)2-3 as a transgene in transgenic fish enhances resistance to Vibrio vulnificus infection and causes variations in immune-related genes after infection by different bacterial species. Fish & shellfish immunology. 29(3):430-439
Peng, K.C., Pan, C.Y., Chou, H.N., and Chen, J.Y. (2010) Using an improved Tol2 transposon system to produce transgenic zebrafish with epinecidin-1 which enhanced resistance to bacterial infection. Fish & shellfish immunology. 28(5-6):905-917
Amsterdam, A., Nissen, R.M., Sun, Z., Swindell, E., Farrington, S., and Hopkins, N. (2004) Identification of 315 genes essential for early zebrafish development. Proceedings of the National Academy of Sciences of the United States of America. 101(35):12792-12797
Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J., and Marra,M.A. (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proceedings of the National Academy of Sciences of the United States of America. 99(26):16899-903
Additional Citations (24):
ZFIN Staff (2024) Association of Ensembl transcripts with ZFIN genes. Semi-automated Curation.
ZFIN Staff (2023) Automated Curation of UniProt Database Links. Automated Data Submission.
ZFIN Staff (2020) Addition of links from ZFIN to Expression Atlas. Semi-automated Curation.
ZFIN Staff (2019) Analysis of data directly submitted to the Zebrafish International Resource Center (ZIRC). ZFIN Direct Data Submission.
ZFIN Staff (2017) Curation of PANTHER Gene IDs. Automated Data Submission.
ZFIN Staff (2017) Curation of Alliance of Genome Resources Database Links. Automated Data Submission.
ZFIN Staff (2015) Data Model Change: Sequence Targeting Reagents Removed from Environment. ZFIN Historical Data.
Busch-Nentwich, E., Kettleborough, R., Dooley, C. M., Scahill, C., Sealy, I., White, R., Herd, C., Mehroke, S., Wali, N., Carruthers, S., Hall, A., Collins, J., Gibbons, R., Pusztai, Z., Clark, R., and Stemple, D.L. (2013) Sanger Institute Zebrafish Mutation Project mutant data submission. ZFIN Direct Data Submission.
ZFIN Staff (2013) Semi-automated association of ENSDARG identifiers with ZFIN genes for the ZMP project. Semi-automated Curation.
ZIRC and ZFIN staff (2013) Mutant and Transgenic Line Submissions 2013. ZFIN Direct Data Submission.
Gaudet, P., Livstone, M., Thomas, P., The Reference Genome Project (2010) Annotation inferences using phylogenetic trees. Automated Data Submission.
ZIRC and ZFIN Staff (2008) Mutant and Transgenic Line Submissions 2008. ZFIN Direct Data Submission.
ZFIN Staff (2007) Microarray Expression to Gene Association in ZFIN. Semi-automated Curation.
Phenotype Annotation (1994-2006) (2006) Mutant Data Curated from Older Literature. ZFIN Historical Data.
ZFIN Staff (2006) Curation of Ensembl Database Links. Automated Data Submission.
Thisse, B., Thisse, C. (2004) Fast Release Clones: A High Throughput Expression Analysis. ZFIN Direct Data Submission.
ZFIN Staff (2004) ZGC Data Curation and Association in ZFIN by ZFIN Staff. Semi-automated Curation.
Zebrafish Nomenclature Committee (2003) Nomenclature Data Curation (2003-2010). Nomenclature Committee Submission.
ZFIN Staff (2003) Submission and Curation of Mutant and Transgenic Lines. ZFIN Direct Data Submission.
ZFIN Staff (2003) Curation of VEGA Database Links. Automated Data Submission.
ZFIN Staff (2003) Curation of orthology data. Manually curated data.
ZFIN Staff (2002) Curation of NCBI Gene Data Via Shared RNA Sequence IDs. Automated Data Submission.
ZFIN Staff (2002) Scientific Curation. Manually curated data.
ZFIN Staff (2002) Gene Ontology Annotation Through Association of InterPro Records with GO Terms. Automated Data Submission.
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