Gene

nkap

ID
ZDB-GENE-030131-8064
Name
NFKB activating protein
Symbol
nkap Nomenclature History
Previous Names
  • nkapl
  • c6orf194l (1)
  • FLJ22626-like (1)
  • wu:fj36d09
  • wu:fj49c09
  • zgc:136458
Type
protein_coding_gene
Location
Chr: 14 Mapping Details/Browsers
Description
Predicted to have chromatin binding activity. Predicted to be involved in Notch signaling pathway and negative regulation of transcription, DNA-templated. Orthologous to several human genes including NKAP (NFKB activating protein).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
6 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
5 figures from 3 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With nkap Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Intellectual developmental disorder, X-linked, syndromic, Hackman-Di Donato type 301039
Associated With nkap Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR009269 NF-kappa-B-activating protein, C-terminal
Family IPR040466 NF-kappa-B-activating protein
Domain Details Per Protein
Protein Length NF-kappa-B-activating protein NF-kappa-B-activating protein, C-terminal
UniProtKB:E7F275 251
UniProtKB:Q1ED01 136
UniProtKB:Q6DRM1 368
UniProtKB:F1R4A9 136
UniProtKB:E7F248 328
UniProtKB:A0A2R8PWL5 130
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Note
Amsterdam, et al. (2004. Proc. Natl. Acad. Sci. USA 101:12792-12797) reported this gene to be the ortholog of human NKAPL based on amino acid similarity. Subsequent analysis suggests it is the ortholog of human NKAP and mouse Nkap based on amino acid sequence and conserved synteny.
Citations