ZFIN

ZFIN ID: ZDB-GENE-020829-1

ZFIN ID: ZDB-GENE-020829-1

CITATIONS (61 total)

Gene Name:	SIM bHLH transcription factor 1a
Gene Symbol:	sim1a

Zhang, Q., Li, F., Li, T., Lin, J., Jian, J., Zhang, Y., Chen, X., Liu, T., Gou, S., Zhang, Y., Liu, X., Ji, Y., Wang, X., Li, Q. (2024) Nomo1 deficiency causes autism-like behavior in zebrafish. EMBO reports. 25(2):570-592

England, S.J., Rusnock, A.K., Mujcic, A., Kowalchuk, A., de Jager, S., Hilinski, W.C., Juárez-Morales, J.L., Smith, M.E., Grieb, G., Banerjee, S., Lewis, K.E. (2023) Molecular analyses of zebrafish V0v spinal interneurons and identification of transcriptional regulators downstream of Evx1 and Evx2 in these cells. Neural Development. 18:88

Böhm, U.L., Kimura, Y., Kawashima, T., Ahrens, M.B., Higashijima, S.I., Engert, F., Cohen, A.E. (2022) Voltage imaging identifies spinal circuits that modulate locomotor adaptation in zebrafish. Neuron. 110(7):1211-1222.e4

Jacobs, C.T., Kejriwal, A., Kocha, K.M., Jin, K.Y., Huang, P. (2022) Temporal cell fate determination in the spinal cord is mediated by the duration of Notch signalling. Developmental Biology. 489:1-13

Wang, R., Guo, S., Yang, L. (2022) Tal2 is required for generation of GABAergic neurons in the zebrafish midbrain. Developmental Dynamics : an official publication of the American Association of Anatomists. 252(2):263-275

Westphal, M., Panza, P., Kastenhuber, E., Wehrle, J., Driever, W. (2022) Wnt/β-catenin signaling promotes neurogenesis in the diencephalospinal dopaminergic system of embryonic zebrafish. Scientific Reports. 12:1030

Chu, S., Kwon, B.R., Lee, Y.M., Zoh, K.D., Choi, K. (2021) Effects of 2-ethylhexyl-4-methoxycinnamate (EHMC) on thyroid hormones and genes associated with thyroid, neurotoxic, and nephrotoxic responses in adult and larval zebrafish (Danio rerio). Chemosphere. 263:128176

Danesin, C., Darche-Gabinaud, R., Escalas, N., Bouguetoch, V., Cochard, P., Al Oustah, A., Ohayon, D., Glise, B., Soula, C. (2021) Sulf2a controls Shh-dependent neural fate specification in the developing spinal cord. Scientific Reports. 11:118

Hsieh, Y.W., Tsai, Y.W., Lai, H.H., Lai, C.Y., Lin, C.Y., Her, G.M. (2021) Depletion of Alpha-Melanocyte-Stimulating Hormone Induces Insatiable Appetite and Gains in Energy Reserves and Body Weight in Zebrafish. Biomedicines. 9(8):

Mukaigasa, K., Sakuma, C., Yaginuma, H. (2021) The developmental hourglass model is applicable to the spinal cord based on single-cell transcriptomes and non-conserved cis-regulatory elements. Development, growth & differentiation. 63(7):372-391

Andrzejczuk, L.A., Banerjee, S., England, S.J., Voufo, C., Kamara, K., Lewis, K.E. (2018) Tal1, Gata2a, and Gata3 Have Distinct Functions in the Development of V2b and Cerebrospinal Fluid-Contacting KA Spinal Neurons. Frontiers in neuroscience. 12:170

Chambers, J.M., Poureetezadi, S.J., Addiego, A., Lahne, M., Wingert, R.A. (2018) ppargc1a controls nephron segmentation during zebrafish embryonic kidney ontogeny. eLIFE. 7:

Morales, E.E., Handa, N., Drummond, B.E., Chambers, J.M., Marra, A.N., Addiego, A., Wingert, R.A. (2018) Homeogene emx1 is required for nephron distal segment development in zebrafish. Scientific Reports. 8:18038

Spikol, E.D., Glasgow, E. (2018) Separate roles for Med12 and Wnt signaling in regulation of oxytocin expression. Biology Open. 7(3)

Drummond, B.E., Li, Y., Marra, A.N., Cheng, C.N., Wingert, R.A. (2017) The tbx2a/b transcription factors direct pronephros segmentation and corpuscle of Stannius formation in zebrafish. Developmental Biology. 421(1):52-66

Kondrychyn, I., Robra, L., Thirumalai, V. (2017) Transcriptional Complexity and Distinct Expression Patterns of auts2 Paralogs in Danio rerio.. G3 (Bethesda). 7(8):2577-2593

Kasher, P.R., Schertz, K.E., Thomas, M., Jackson, A., Annunziata, S., Ballesta-Martinez, M.J., Campeau, P.M., Clayton, P.E., Eaton, J.L., Granata, T., Guillén-Navarro, E., Hernando, C., Laverriere, C.E., Liedén, A., Villa-Marcos, O., McEntagart, M., Nordgren, A., Pantaleoni, C., Pebrel-Richard, C., Sarret, C., Sciacca, F.L., Wright, R., Kerr, B., Glasgow, E., Banka, S. (2016) Small 6q16.1 Deletions Encompassing POU3F2 Cause Susceptibility to Obesity and Variable Developmental Delay with Intellectual Disability. American journal of human genetics. 98(2):363-72

Poureetezadi, S.J., Cheng, C.N., Chambers, J.M., Drummond, B.E., Wingert, R.A. (2016) Prostaglandin signaling regulates nephron segment patterning of renal progenitors during zebrafish kidney development. eLIFE. 5

Affaticati, P., Yamamoto, K., Rizzi, B., Bureau, C., Peyriéras, N., Pasqualini, C., Demarque, M., Vernier, P. (2015) Identification of the optic recess region as a morphogenetic entity in the zebrafish forebrain. Scientific Reports. 5:8738

Cheng, C.N., Wingert, R.A. (2015) Nephron proximal tubule patterning and corpuscles of Stannius formation are regulated by the sim1a transcription factor and retinoic acid in zebrafish. Developmental Biology. 399(1):100-16

Al Oustah, A., Danesin, C., Khouri-Farah, N., Farreny, M.A., Escalas, N., Cochard, P., Glise, B., and Soula, C. (2014) Dynamics of Sonic hedgehog signaling in the ventral spinal cord are controlled by intrinsic changes in source cells requiring Sulfatase 1. Development (Cambridge, England). 141(6):1392-1403

Koch, P., Löhr, H.B., Driever, W. (2014) A Mutation in cnot8, Component of the Ccr4-Not Complex Regulating Transcript Stability, Affects Expression Levels of Developmental Regulators and Reveals a Role of Fgf3 in Development of Caudal Hypothalamic Dopaminergic Neurons. PLoS One. 9:e113829

Schweitzer, J., Löhr, H., Bonkowsky, J.L., Hübscher, K., and Driever, W. (2013) Sim1a and Arnt2 contribute to hypothalamo-spinal axon guidance by regulating Robo2 activity via a Robo3-dependent mechanism. Development (Cambridge, England). 140(1):93-106

Wolf, A., and Ryu, S. (2013) Specification of posterior hypothalamic neurons requires coordinated activities of Fezf2, Otp, Sim1a and Foxb1.2. Development (Cambridge, England). 140(8):1762-1773

Lauter, G., Soll, I., and Hauptmann, G. (2011) Two-color fluorescent in situ hybridization in the embryonic zebrafish brain using differential detection systems. BMC Developmental Biology. 11(1):43

Mahler, J., Filippi, A., and Driever, W. (2010) DeltaA/DeltaD Regulate Multiple and Temporally Distinct Phases of Notch Signaling during Dopaminergic Neurogenesis in Zebrafish. The Journal of neuroscience : the official journal of the Society for Neuroscience. 30(49):16621-16635

Yang, L., Rastegar, S., and Strähle, U. (2010) Regulatory interactions specifying Kolmer-Agduhr interneurons. Development (Cambridge, England). 137(16):2713-2722

Borodovsky, N., Ponomaryov, T., Frenkel, S., and Levkowitz, G. (2009) Neural protein Olig2 acts upstream of the transcriptional regulator sim1 to specify diencephalic dopaminergic neurons. Developmental Dynamics : an official publication of the American Association of Anatomists. 238(4):826-834

Hill, A.J., Heiden, T.C., Heideman, W., and Peterson, R.E. (2009) Potential roles of arnt2 in zebrafish larval development. Zebrafish. 6(1):79-91

Lam, P.Y., Webb, S.E., Leclerc, C., Moreau, M., and Miller, A.L. (2009) Inhibition of stored Ca release disrupts convergence-related cell movements in the lateral intermediate mesoderm resulting in abnormal positioning and morphology of the pronephric anlagen in intact zebrafish embryos. Development, growth & differentiation. 51(4):429-442

Löhr, H., Ryu, S., and Driever, W. (2009) Zebrafish diencephalic A11-related dopaminergic neurons share a conserved transcriptional network with neuroendocrine cell lineages. Development (Cambridge, England). 136(6):1007-1017

Eaton, J.L., Holmqvist, B., and Glasgow, E. (2008) Ontogeny of vasotocin-expressing cells in zebrafish: Selective requirement for the transcriptional regulators orthopedia and single-minded 1 in the preoptic area. Developmental Dynamics : an official publication of the American Association of Anatomists. 237(4):995-1005

Sanek, N.A., and Grinblat, Y. (2008) A novel role for zebrafish zic2a during forebrain development. Developmental Biology. 317(1):325-335

Eaton, J.L., and Glasgow, E. (2007) Zebrafish orthopedia (otp) is required for isotocin cell development. Development genes and evolution. 217(2):149-158

Schafer, M., Kinzel, D., and Winkler, C. (2007) Discontinuous organization and specification of the lateral floor plate in zebrafish. Developmental Biology. 301(1):117-129

Eaton, J.L., and Glasgow, E. (2006) The zebrafish bHLH PAS transcriptional regulator, single-minded 1 (sim1), is required for isotocin cell development. Developmental Dynamics : an official publication of the American Association of Anatomists. 235(8):2071-2082

Van Campenhout, C., Nichane, M., Antoniou, A., Pendeville, H., Bronchain, O.J., Marine, J.C., Mazabraud, A., Voz, M.L., and Bellefroid, E.J. (2006) Evi1 is specifically expressed in the distal tubule and duct of the Xenopus pronephros and plays a role in its formation. Developmental Biology. 294(1):203-219

Woods, I.G., Wilson, C., Friedlander, B., Chang, P., Reyes, D.K., Nix, R., Kelly, P.D., Chu, F., Postlethwait, J.H., and Talbot, W.S. (2005) The zebrafish gene map defines ancestral vertebrate chromosomes. Genome research. 15(9):1307-1314

Hill, A.J., Bello, S.M., Prasch, A.L., Peterson, R.E., and Heideman, W. (2004) Water permeability and TCDD-induced edema in zebrafish early-life stages. Toxicological sciences : an official journal of the Society of Toxicology. 78(1):78-87

Serluca, F.C. and Fishman, M.C. (2001) Pre-pattern in the pronephric kidney field of zebrafish. Development (Cambridge, England). 128(12):2233-2241

Additional Citations (21):

ZFIN Staff (2024) Association of Ensembl transcripts with ZFIN genes. Semi-automated Curation.

ZFIN Staff (2023) Automated Curation of UniProt Database Links. Automated Data Submission.

ZFIN Staff (2022) Electronic Gene Ontology annotations created by ARBA machine learning models. Automated Data Submission.

ZFIN Staff (2020) Addition of links from ZFIN to Expression Atlas. Semi-automated Curation.

ZFIN Staff (2017) Curation of PANTHER Gene IDs. Automated Data Submission.

ZFIN Staff (2017) Curation of Alliance of Genome Resources Database Links. Automated Data Submission.

UniProt curators (2015) Electronic Gene Ontology annotations created by transferring manual GO annotations between related proteins based on shared sequence features.. Automated Data Submission.

Busch-Nentwich, E., Kettleborough, R., Dooley, C. M., Scahill, C., Sealy, I., White, R., Herd, C., Mehroke, S., Wali, N., Carruthers, S., Hall, A., Collins, J., Gibbons, R., Pusztai, Z., Clark, R., and Stemple, D.L. (2013) Sanger Institute Zebrafish Mutation Project mutant data submission. ZFIN Direct Data Submission.

ZFIN Staff (2013) Semi-automated association of ENSDARG identifiers with ZFIN genes for the ZMP project. Semi-automated Curation.

UniProt-GOA (2011) Gene Ontology annotation based on the manual assignment of UniProtKB Subcellular Location terms in UniProtKB/Swiss-Prot entries. Manually curated data.

UniProt-GOA (2011) Gene Ontology annotation based on the automatic assignment of UniProtKB Subcellular Location terms in UniProtKB/TrEMBL entries. Manually curated data.

Gaudet, P., Livstone, M., Thomas, P., The Reference Genome Project (2010) Annotation inferences using phylogenetic trees. Automated Data Submission.

GOA curators, UniProt curators (2007) Gene Ontology annotation based on Swiss-Prot Subcellular Location vocabulary mapping. Manually curated data.

ZFIN Staff (2007) Microarray Expression to Gene Association in ZFIN. Semi-automated Curation.

ZFIN Staff (2006) Curation of Ensembl Database Links. Automated Data Submission.

ZFIN Staff (2003) Curation of VEGA Database Links. Automated Data Submission.

ZFIN Staff (2003) Curation of orthology data. Manually curated data.

ZFIN Staff (2002) Gene Ontology Annotation Through Association of UniProt Keywords with GO Terms. Automated Data Submission.

ZFIN Staff (2002) Curation of NCBI Gene Data Via Shared RNA Sequence IDs. Automated Data Submission.

ZFIN Staff (2002) Scientific Curation. Manually curated data.

ZFIN Staff (2002) Gene Ontology Annotation Through Association of InterPro Records with GO Terms. Automated Data Submission.