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Phenotype Figure Summary
Marker:
mir126a
Conditions:
Standard or Control
Publication
Data
Fish
Anatomy
Chen
et al.
, 2016
Fig. 1
y1Tg + CRISPR1-mir126a + CRISPR2-mir126a
, 
y1Tg + MO1-mir126a
lymphangioblast cord broken, abnormal
lymphangioblast cord hypoplastic, abnormal
lymphangiogenesis disrupted, abnormal
thoracic duct absent, abnormal
thoracic duct hypoplastic, abnormal
vascular lymphangioblast absent, abnormal
Fig. 3
y1Tg + MO1-mir126a
lymphangioblast cord absent, abnormal
lymphangiogenesis disrupted, abnormal
lymphangiogenic sprout absent, abnormal
lymphatic endothelial cell migration disrupted, abnormal
vascular lymphangioblast absent, abnormal
Fig. 4
TU + MO1-mir126a
horizontal myoseptum
cxcl12a
expression decreased distribution, abnormal
horizontal myoseptum Ab1-cxcl12 labeling decreased distribution, abnormal
Fig. 5
y1Tg + MO1-mir126a
, 
TU + MO1-mir126a
lymphangiogenesis disrupted, abnormal
posterior cardinal vein lymphangiogenic sprout absent, abnormal
posterior cardinal vein lymphangiogenic sprout decreased amount, abnormal
posterior cardinal vein vascular sprouts
tek
expression decreased distribution, abnormal
Fig. 6
y1Tg + MO1-mir126a
thoracic duct decreased length, abnormal
thoracic duct hypoplastic, abnormal
vascular lymphangioblast decreased amount, abnormal
Fig. S5
y1Tg + CRISPR1-mir126a + CRISPR2-mir126a
, 
y1Tg + CRISPR1-mir126a + CRISPR4-mir126a
lymphangioblast cord decreased length, abnormal
thoracic duct absent, abnormal
vascular lymphangioblast decreased amount, abnormal
Sessa
et al.
, 2012
Fig. 2
s843Tg + MO4-mir126a
atrial myocardium decreased size, abnormal
dorsal aorta decreased diameter, abnormal
heart morphology, abnormal
intersegmental vessel deformed, abnormal
myocardium decreased size, abnormal
whole organism edematous, abnormal
Zou
et al.
, 2011
Fig. 5
y1Tg + MO1-mir126a
cranium hemorrhagic, abnormal
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