Publication	Data		Fish	Anatomy
Lin et al., 2021	Fig. 1		cftrscu102/scu102	thymic epithelium ccl25a expression decreased amount, abnormal thymic epithelium foxn1 expression decreased amount, abnormal thymus ccr9a expression decreased amount, abnormal thymus rag1 expression decreased amount, abnormal thymus rag2 expression decreased amount, abnormal
	Fig. S1		cftrscu102/scu102	thymus rag1 expression decreased amount, abnormal
	Fig. S2		cftrscu102/scu102	macrophage csf1ra expression decreased amount, abnormal neutrophil mpx expression decreased amount, abnormal
Cafora et al., 2020	Fig. 1		AB + MO1-cftr + MO2-cftr	determination of liver left/right asymmetry disrupted, abnormal determination of pancreatic left/right asymmetry disrupted, abnormal heart looping disrupted, abnormal heart mislocalised, abnormal
Liu et al., 2020	Fig. 1		cftrscu101/scu101	atrium dilated, abnormal heart bmp4 expression decreased distribution, abnormal heart has2 expression decreased distribution, abnormal heart contraction decreased rate of occurrence, abnormal heart dysplastic, abnormal heart edematous, abnormal heart looping process quality, abnormal lateral mesoderm nkx2.5 expression decreased distribution, abnormal whole organism bmp4 expression decreased amount, abnormal whole organism has2 expression decreased amount, abnormal whole organism nkx2.5 expression decreased amount, abnormal
	Fig. 3		cftrscu101/scu101	whole organism atp2a2a expression decreased amount, abnormal whole organism cacna2d2a expression decreased amount, abnormal whole organism hip1ra expression decreased amount, abnormal whole organism itga10 expression decreased amount, abnormal whole organism itgb1b.1 expression increased amount, abnormal whole organism itgbl1 expression decreased amount, abnormal whole organism mamdc2b expression increased amount, abnormal whole organism si:ch211-211k8.4 expression decreased amount, abnormal whole organism smyhc2 expression increased amount, abnormal whole organism tpm4b expression increased amount, abnormal
	Fig. 4		cftrscu101/scu101	lateral mesoderm nkx2.5 expression decreased distribution, abnormal
Liu et al., 2020	Fig. 1		cftrscu102/scu102 (AB)	endoderm sox17 expression decreased distribution, abnormal forerunner cell group sox17 expression decreased distribution, abnormal gastrula cell gata2a expression decreased distribution, abnormal gastrula cell ventral region bmp4 expression decreased distribution, abnormal gastrula cell ventral region eve1 expression decreased distribution, abnormal mesoderm tbxta expression decreased distribution, abnormal neuroectoderm anterior region otx2b expression decreased distribution, abnormal shield chrd expression decreased distribution, abnormal shield gsc expression decreased distribution, abnormal
	Fig. 2		cftrscu102/scu102 (AB)	somite myod1 expression decreased distribution, abnormal
	Fig. 3		cftrscu102/scu102 (AB)	shield chrd expression decreased distribution, abnormal shield gsc expression decreased distribution, abnormal
Bernut et al., 2019	Fig. S3		i114Tg + MO7-cftr	neutrophil increased amount, abnormal
Cafora et al., 2019	Fig. 2		AB + MO1-cftr + MO2-cftr	determination of liver left/right asymmetry decreased occurrence, abnormal determination of pancreatic left/right asymmetry decreased occurrence, abnormal heart looping decreased occurrence, abnormal
	Fig. 4		AB + MO1-cftr + MO2-cftr	whole organism il1b expression increased amount, abnormal whole organism tnfa expression increased amount, abnormal
Liao et al., 2018	Fig. 1		cftrscu101/scu101 (AB)	Kupffer's vesicle development arrested, abnormal tail bud lacks all parts of type Kupffer's vesicle, abnormal whole organism cftr expression decreased amount, abnormal
	Fig. 2		cftrscu101/scu101 (AB)	germ cell migration decreased occurrence, abnormal primordial germ cell mislocalised, abnormal
	Fig. 4		cftrscu101/scu101 (AB)	germ cell migration decreased occurrence, abnormal primordial germ cell mislocalised, abnormal
	Fig. 5		cftrscu101/scu101 (AB)	germ cell migration decreased occurrence, abnormal primordial germ cell mislocalised, abnormal whole organism ca15b expression increased amount, abnormal whole organism cxcl12a expression increased amount, abnormal whole organism cxcr4b expression increased amount, abnormal whole organism rgs14a expression increased amount, abnormal
Sun et al., 2018	Fig. 1		cftrscu102/+	lateral plate mesoderm gata1a expression decreased distribution, abnormal lateral plate mesoderm tal1 expression decreased amount, abnormal
	Fig. 2		cftrscu102/+	common myeloid progenitor myb expression decreased amount, abnormal common myeloid progenitor runx1 expression decreased amount, abnormal erythroid lineage cell hbbe3 expression decreased amount, abnormal intermediate cell mass of mesoderm hbbe3 expression decreased amount, abnormal intermediate cell mass of mesoderm myb expression decreased amount, abnormal intermediate cell mass of mesoderm runx1 expression decreased amount, abnormal lateral plate mesoderm gata1a expression decreased amount, abnormal lateral plate mesoderm gata2a expression decreased amount, abnormal lateral plate mesoderm lmo2 expression decreased amount, abnormal lateral plate mesoderm tal1 expression decreased amount, abnormal myeloid lineage restricted progenitor cell spi1b expression decreased amount, abnormal
	Fig. 3		cftrscu102/+ ,   AB + MO2-cftr	lateral plate mesoderm gata1a expression decreased amount, abnormal lateral plate mesoderm tal1 expression decreased amount, abnormal mesoderm cdx4 expression decreased amount, abnormal mesoderm hoxa9a expression decreased amount, abnormal whole organism dvl2 expression decreased amount, abnormal whole organism dvl3a expression decreased amount, abnormal whole organism lef1 expression decreased amount, abnormal whole organism myca expression decreased amount, abnormal
	Fig. S10		AB + MO2-cftr	common myeloid progenitor myb expression decreased amount, abnormal common myeloid progenitor runx1 expression decreased amount, abnormal erythroid lineage cell hbbe3 expression decreased amount, abnormal intermediate cell mass of mesoderm hbbe3 expression decreased amount, abnormal intermediate cell mass of mesoderm myb expression decreased amount, abnormal intermediate cell mass of mesoderm runx1 expression decreased amount, abnormal lateral plate mesoderm gata1a expression decreased amount, abnormal lateral plate mesoderm gata2a expression decreased amount, abnormal lateral plate mesoderm lmo2 expression decreased amount, abnormal lateral plate mesoderm tal1 expression decreased amount, abnormal myeloid lineage restricted progenitor cell spi1b expression decreased amount, abnormal
	Fig. S12		AB + MO2-cftr	mesoderm cdx4 expression decreased amount, abnormal mesoderm hoxa9a expression decreased amount, abnormal
	Fig. S14		AB + MO2-cftr	lateral plate mesoderm gata1a expression decreased amount, abnormal lateral plate mesoderm tal1 expression decreased amount, abnormal
	Fig. S16		cftrscu102/+	common myeloid progenitor myb expression decreased amount, abnormal common myeloid progenitor runx1 expression decreased amount, abnormal intermediate cell mass of mesoderm myb expression decreased amount, abnormal intermediate cell mass of mesoderm runx1 expression decreased amount, abnormal
	Fig. S18		cftrscu102/+	common myeloid progenitor myb expression decreased amount, abnormal common myeloid progenitor runx1 expression decreased amount, abnormal intermediate cell mass of mesoderm myb expression decreased amount, abnormal intermediate cell mass of mesoderm runx1 expression decreased amount, abnormal
	Fig. S6		cftrscu102/+ ,   AB + MO2-cftr	common myeloid progenitor tal1 expression decreased amount, abnormal erythroid lineage cell gata1a expression decreased amount, abnormal myeloid cell lcp1 expression decreased amount, abnormal
	Fig. S7		AB + MO2-cftr ,   AB + MO6-cftr	lateral plate mesoderm tal1 expression decreased amount, abnormal
Ji et al., 2016	Fig. 7		cftrpd1048/pd1048 (AB/TU)	brain elovl6 expression spatial pattern, abnormal brain right side elovl6 expression mislocalised, abnormal left/right pattern formation disrupted, abnormal
Delaspre et al., 2015	Fig. 7		cftrpd1049/pd1049	pancreas decreased size, abnormal pancreatic centroacinar cell decreased amount, abnormal secondary islet cell decreased amount, abnormal
	Fig. S5		cftrpd1049/pd1049	Kupffer's vesicle absent, abnormal
Navis et al., 2015	Fig. 4		cftrpd1049/pd1049; gz15Tg	pancreas degenerate, abnormal pancreas lacks parts or has fewer parts of type pancreatic acinar cell, abnormal pancreatic acinar cell decreased amount, abnormal
	Fig. 5		cftrpd1049/pd1049 (AB) ,   cftrpd1049/pd1049; gz15Tg; m1018Tg	exocrine pancreas central region lacks all parts of type pancreatic acinar cell, abnormal exocrine pancreas degenerate, abnormal exocrine pancreas fibrillary, abnormal islet decreased size, abnormal islet disorganized, abnormal islet increased amount, abnormal pancreas degenerate, abnormal pancreas morphology, abnormal pancreatic acinar cell decreased amount, abnormal pancreatic duct dilated, abnormal pancreatic duct obstructed, abnormal
	Fig. 6		cftrpd1049/pd1049; gz15Tg ,   cftrpd1049/pd1049; nz50Tg	neutrophil migration increased occurrence, abnormal pancreas degenerate, abnormal pancreas neutrophil mislocalised, abnormal pancreatic acinar cell decreased amount, abnormal
Navis et al., 2013	Fig. 2		cftrpd1049/pd1049; gz15Tg ,   cftrpd1049/pd1049	determination of heart left/right asymmetry decreased process quality, abnormal determination of left/right symmetry decreased process quality, abnormal determination of liver left/right asymmetry decreased process quality, abnormal heart looping decreased process quality, abnormal heart mislocalised, abnormal liver mislocalised, abnormal
	Fig. 3		cftrpd1050/pd1050 ,   cftrpd1048/pd1048 ,   cftrpd1048/pd1048; s870Tg ,   cftrpd1049/pd1049; s870Tg ,   cftrpd1049/pd1049	Kupffer's vesicle decreased volume, abnormal Kupffer's vesicle development decreased process quality, abnormal Kupffer's vesicle unlumenized, abnormal
	Fig. 8		cftrpd1049/pd1049	Kupffer's vesicle decreased volume, abnormal Kupffer's vesicle development decreased process quality, abnormal Kupffer's vesicle unlumenized, abnormal
Phennicie et al., 2010	Fig. 2		AB + MO1-cftr + MO2-cftr	respiratory burst involved in inflammatory response disrupted, abnormal