ZFIN ID: ZDB-FIG-220331-47
Liu et al., 2020 - CFTR deficiency causes cardiac dysplasia during zebrafish embryogenesis and is associated with dilated cardiomyopathy. Mechanisms of Development   163:103627 Full text @ Mech. Dev.
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Fish:
Anatomical Term:
Stage Range: 128-cell to Dome
PHENOTYPE:
Fish:
Observed In:
Stage Range: 128-cell to Dome

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Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
atp2a2a WT standard conditions 128-cell to Dome whole organism RTPCR
cftrscu101/scu101 standard conditions 128-cell to Dome whole organism RTPCR
cacna2d2a WT standard conditions 128-cell to Dome whole organism RTPCR
cftrscu101/scu101 standard conditions 128-cell to Dome whole organism RTPCR
hip1ra WT standard conditions 128-cell to Dome whole organism RTPCR
cftrscu101/scu101 standard conditions 128-cell to Dome whole organism RTPCR
itga10 WT standard conditions 128-cell to Dome whole organism RTPCR
cftrscu101/scu101 standard conditions 128-cell to Dome whole organism RTPCR
itgb1b.1 WT standard conditions 128-cell to Dome whole organism RTPCR
cftrscu101/scu101 standard conditions 128-cell to Dome whole organism RTPCR
itgbl1 WT standard conditions 128-cell to Dome whole organism RTPCR
cftrscu101/scu101 standard conditions 128-cell to Dome whole organism RTPCR
mamdc2b WT standard conditions 128-cell to Dome whole organism RTPCR
cftrscu101/scu101 standard conditions 128-cell to Dome whole organism RTPCR
si:ch211-211k8.4 WT standard conditions 128-cell to Dome whole organism RTPCR
cftrscu101/scu101 standard conditions 128-cell to Dome whole organism RTPCR
smyhc2 WT standard conditions 128-cell to Dome whole organism RTPCR
cftrscu101/scu101 standard conditions 128-cell to Dome whole organism RTPCR
tpm4b WT standard conditions 128-cell to Dome whole organism RTPCR
cftrscu101/scu101 standard conditions 128-cell to Dome whole organism RTPCR
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
cftrscu101/scu101 standard conditions 128-cell - Dome whole organism atp2a2a expression decreased amount, abnormal
128-cell - Dome whole organism cacna2d2a expression decreased amount, abnormal
128-cell - Dome whole organism hip1ra expression decreased amount, abnormal
128-cell - Dome whole organism itga10 expression decreased amount, abnormal
128-cell - Dome whole organism itgb1b.1 expression increased amount, abnormal
128-cell - Dome whole organism itgbl1 expression decreased amount, abnormal
128-cell - Dome whole organism mamdc2b expression increased amount, abnormal
128-cell - Dome whole organism si:ch211-211k8.4 expression decreased amount, abnormal
128-cell - Dome whole organism smyhc2 expression increased amount, abnormal
128-cell - Dome whole organism tpm4b expression increased amount, abnormal
Acknowledgments:
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Reprinted from Mechanisms of Development, 163, Liu, Y., Lin, Z., Liu, M., Liao, H., Chen, Y., Zhang, X., Chan, H.C., Zhou, B., Rao, L., Sun, H., CFTR deficiency causes cardiac dysplasia during zebrafish embryogenesis and is associated with dilated cardiomyopathy, 103627, Copyright (2020) with permission from Elsevier. Full text @ Mech. Dev.