Morpholino

MO4-six1b

ID

ZDB-MRPHLNO-081211-1

Name

MO4-six1b

Previous Names

UM (1)

Target

six1b (1)

Sequence

5' - TCTCCTCTGGATGCTACGAAGGAAG - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Genomic Features

No data available

Expression

Gene expression in Wild Types + MO4-six1b

Expressed Gene	Anatomy	Figures
mespaa	segmental plate	Fig. 3 from Bessarab et al., 2008
myhz1.1	(not) fast muscle cell myofibril slow muscle cell myofibril somite	Fig. 6 from Bessarab et al., 2008
mylpfa	fast muscle cell myofibril somite whole organism	Fig. 6 from Bessarab et al., 2008
myog	adaxial cell fast muscle cell segmental plate somite	Fig. 2 from O'Brien et al., 2014 Fig. 3 , Fig. 4 from Bessarab et al., 2008
smyhc1	slow muscle cell	Fig. 3 from Bessarab et al., 2008
tpma	(not) fast muscle cell myofibril slow muscle cell myofibril somite	Fig. S2 from O'Brien et al., 2014 Fig. 6 from Bessarab et al., 2008

Phenotype

Phenotype resulting from MO4-six1b

Phenotype	Fish	Figures
cephalic musculature skeletal muscle tissue development decreased process quality, abnormal	i135Tg + MO4-six1b	Fig. 2 from Nord et al., 2013
fast muscle cell shape, abnormal	AB + MO4-six1b	Fig. 7 from Bessarab et al., 2008
fast muscle cell muscle cell development decreased process quality, abnormal	i135Tg + MO4-six1b + MO4-tp53	Fig. 2 from Nord et al., 2013
fast muscle cell myofibril position, abnormal	AB + MO4-six1b	Fig. 7 from Bessarab et al., 2008
skeletal muscle cell apoptotic process increased process quality, abnormal	WT + MO4-six1b	Fig. 2 from O'Brien et al., 2014
skeletal muscle cell proliferation increased rate, abnormal	AB + MO4-six1b	Fig. S2 from Bessarab et al., 2008
skeletal myofibril assembly disrupted, abnormal	AB + MO4-six1b	Fig. 7 from Bessarab et al., 2008
somite U-shaped, abnormal	AB + MO4-six1b	Fig. 7 from Bessarab et al., 2008
somite cell population proliferation decreased occurrence, abnormal	WT + MO4-six1b	Fig. 5 from Nord et al., 2013
somite fast muscle cell disorganized, abnormal	AB + MO4-six1b	Fig. 7 from Bessarab et al., 2008
somitomeric trunk muscle development disrupted, abnormal	AB + MO4-six1b	Fig. 3 , Fig. 4 , Fig. 6 from Bessarab et al., 2008
striated muscle cell differentiation disrupted, abnormal	AB + MO4-six1b	Fig. 3 , Fig. 4 from Bessarab et al., 2008
trunk musculature refractivity, abnormal	AB + MO4-six1b	Fig. 7 from Bessarab et al., 2008

Phenotype of all Fish created by or utilizing MO4-six1b

Phenotype	Fish	Conditions	Figures
striated muscle cell differentiation disrupted, abnormal	AB + MO4-six1b	standard conditions	Fig. 3 , Fig. 4 from Bessarab et al., 2008
skeletal muscle cell proliferation increased rate, abnormal	AB + MO4-six1b	standard conditions	Fig. S2 from Bessarab et al., 2008
trunk musculature refractivity, abnormal	AB + MO4-six1b	standard conditions	Fig. 7 from Bessarab et al., 2008
skeletal myofibril assembly disrupted, abnormal	AB + MO4-six1b	standard conditions	Fig. 7 from Bessarab et al., 2008
somite fast muscle cell disorganized, abnormal	AB + MO4-six1b	standard conditions	Fig. 7 from Bessarab et al., 2008
somitomeric trunk muscle development disrupted, abnormal	AB + MO4-six1b	standard conditions	Fig. 3 , Fig. 4 , Fig. 6 from Bessarab et al., 2008
somite U-shaped, abnormal	AB + MO4-six1b	standard conditions	Fig. 7 from Bessarab et al., 2008
fast muscle cell shape, abnormal	AB + MO4-six1b	standard conditions	Fig. 7 from Bessarab et al., 2008
fast muscle cell myofibril position, abnormal	AB + MO4-six1b	standard conditions	Fig. 7 from Bessarab et al., 2008
somite cell population proliferation decreased occurrence, abnormal	WT + MO4-six1b	standard conditions	Fig. 5 from Nord et al., 2013
skeletal muscle cell apoptotic process increased process quality, abnormal	WT + MO4-six1b	standard conditions	Fig. 2 from O'Brien et al., 2014
somitomeric trunk muscle development disrupted, abnormal	gz5Tg + MO4-six1b	standard conditions	Fig. 6 from Bessarab et al., 2008
cephalic musculature skeletal muscle tissue development decreased process quality, abnormal	i135Tg + MO4-six1b	standard conditions	Fig. 2 from Nord et al., 2013
fast muscle cell muscle cell development decreased process quality, abnormal	i135Tg + MO4-six1b	standard conditions	Fig. 2 from Nord et al., 2013
fast muscle cell muscle cell development decreased process quality, abnormal	i135Tg + MO4-six1b + MO4-tp53	standard conditions	Fig. 2 from Nord et al., 2013
somite cell population proliferation decreased occurrence, abnormal	WT + MO1-six1a + MO4-six1b	standard conditions	Fig. 5 from Nord et al., 2013
somite morphology, abnormal	WT + MO2-six1a + MO4-six1b	standard conditions	Fig. S2 from O'Brien et al., 2014
skeletal muscle cell apoptotic process increased process quality, abnormal	WT + MO2-six1a + MO4-six1b	standard conditions	Fig. 2 from O'Brien et al., 2014
fast muscle cell decreased amount, abnormal	i135Tg + MO1-six1a + MO4-six1b	standard conditions	Fig. 2 from Nord et al., 2013
fast muscle cell muscle cell development decreased process quality, abnormal	i135Tg + MO1-six1a + MO4-six1b	standard conditions	Fig. 2 from Nord et al., 2013
cephalic musculature skeletal muscle tissue development decreased process quality, abnormal	i135Tg + MO1-six1a + MO4-six1b	standard conditions	Fig. 2 from Nord et al., 2013
fast muscle cell muscle cell development decreased process quality, abnormal	i135Tg + MO1-six1a + MO4-six1b + MO4-tp53	standard conditions	Fig. 2 from Nord et al., 2013
fast muscle cell decreased amount, abnormal	i135Tg + MO1-six1a + MO4-six1b + MO4-tp53	standard conditions	Fig. 2 from Nord et al., 2013

Citations