ZFIN Image: Gebuijs et al., 2022, Figure 6

Image

Figure Caption

Figure 6

Relative expression levels in 5 dpf wild type zebrafish larvae treated with 5 �M of BGJ398.

Exposure windows were 0?12 and 24?36 hpf. Exposed fish (n = 8) were compared to a DMSO control (n = 8, final concentration 0.1%). (A) Expression of fgfr s showing differential expression in fgfr1a, fgfr1b, fgfr2 and fgfr4. (B) Expression of genes involved in bone formation. (C) Genes involved in cartilage formation. From col9a1b one outlier (p < 0.01 in Grubbs? test) was removed. (D) Neural crest cell marker genes. All data are presented as box plots, with median represented by a line within the box; interquartile ranges by the boxes, 5?95 confidence intervals by whiskers and means indicated by ?+? symbol. All the data were analyzed using a Kruskal?Wallis test followed by a Dunn?s multiple comparison test. Asterisks indicate significant differences; ^?p < 0.05, ^??p < 0.01, ^???p < 0.001.

Figure Data

Expression / Labeling details

Phenotype details

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Peer J.