Fig. 2 - Supplemental 1
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- ZDB-FIG-260507-6
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- Letelier et al., 2023 - Mutation of vsx genes in zebrafish highlights the robustness of the retinal specification network
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OKR measurements indicate decreased eye movement velocity in vsx mutants. (a-c). OKR was recorded in wildtype (blue), vsx1∆245 (red), vsx2∆73 (green), and vsxKO double mutants (yellow) at 5dpf in response to different contrast (a), spatial frequency (b) and angular velocity (c). OKR is significantly reduced in vsx1∆245 and vsxKO double mutant larvae in comparison to WT siblings (***p<0.001) using a one-way ANOVA. Note that no differences in OKR were observed between WT and vsx2∆73 single mutant or between vsx1∆245 and vsxKO mutants (p>0.05). In (a-c), vsx1∆245 (red tracks) represents both vsx1∆245-/- and vsx1∆245-/-; vsx2∆73+/-genotypes, while vsx2∆73 (green tracks) represents both vsx2∆73-/- and vsx1∆245+/-; vsx2∆73-/- genotypes. In all panels, data is shown as mean ± SEM. deg: degrees, s: seconds. |