Figure 4
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Interaction network of PAHs’ potential targets and their downstream proteins (A) Venn diagram analysis of AD-associated DEGs, AD-associated GeneCards library genes, and potential target protein genes for PAHs. (B) Protein-protein interaction networks (PPI) analysis between predicted PAH targets and AD-associated DEGs. Orange indicates predicted PAH targets; blue and yellow indicate AD-associated DEGs. (C) Using the leading eigenvector algorithm, modularity, and community structure in PPI from predicted PAH targets and AD-associated DEGs. (D) GO enrichment analysis of six modular genes, including biological process, cellular component, and molecular function analysis. (E) KEGG enrichment analysis of six modular genes. |