FIGURE

Fig. 4

ID

ZDB-FIG-260215-169

Publication

Chen et al., 2026 - GJB2 c.109G > A mutation activating IFI27-mediated mitochondrial apoptosis pathway leading to hereditary non-syndromic hearing loss

Other Figures

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Fig. 4

Hair cell staining of zebrafish after GJB2 c.109G > A mutation and knockdown. A. Specific fluorescence staining with 1 mM DASPEI (green) for 2 h, anesthetized with 0.03% MS-222, photographed under a 3× stereofluorescence microscope; B. Quantification of hair cell numbers in different groups of zebrafish using Image J, statistical analysis using GraphPad Prism 10. Blue arrows represent hair cells in the inner ear and red arrows represent hair cells in the lateral line system. n ≥ 10. Each column and bar represent the mean ± SEM. All data were statistically analyzed by one-way ANOVA, * p < 0.05 indicates a significant difference, and *** p < 0.001 indicates an extremely significant difference.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	AB + MO3-gjb8
Knockdown Reagent:	MO3-gjb8
Observed In:	neuromast hair cell
Stage:	Protruding-mouth

Phenotype Detail

Acknowledgments

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