FIGURE

Fig. 2

ID

ZDB-FIG-260215-167

Publication

Chen et al., 2026 - GJB2 c.109G > A mutation activating IFI27-mediated mitochondrial apoptosis pathway leading to hereditary non-syndromic hearing loss

Other Figures

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Fig. 2

Analysis of developmental phenotype changes in zebrafish after GJB2 c.109G > A mutation and knockdown. A. Photograph taken under a 3× stereomicroscope, ventral view, head left, tail right; (B) Statistical chart of yolk sac area in different groups of zebrafish; (C) Percentage of tail coiling in different groups of zebrafish; (D) Percentage of pericardial edema in different groups of zebrafish. n ≥ 10. Each column and bar represent the mean ± SEM. All data were statistically analyzed by one-way ANOVA, * p < 0.05 indicates a significant difference, and *** p < 0.001 indicates an extremely significant difference.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	AB + MO3-gjb8
Knockdown Reagent:	MO3-gjb8
Observed In:	ball pericardium post-vent region
Stage:	Protruding-mouth

Phenotype Detail

Acknowledgments

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