FIGURE

Fig. 3

ID

ZDB-FIG-260215-168

Publication

Chen et al., 2026 - GJB2 c.109G > A mutation activating IFI27-mediated mitochondrial apoptosis pathway leading to hereditary non-syndromic hearing loss

Other Figures

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Fig. 3

Ear structure of zebrafish after GJB2 c.109G > A mutation and knockdown. A. Schematic diagram of zebrafish ear structure; Use Image J software to measure anterior otolith (B), posterior otolith (C), ear spacing (D) and cochlear diameter (E) of zebrafish. n ≥ 10, CD represents cochlea, OD represents interaural distance, AOD represents anterior otolith, POD represents posterior otolith. Each column and bar represent the mean ± SEM. All data were statistically analyzed by one-way ANOVA, * p < 0.05 indicates a significant difference, ** p < 0.01 indicates a very significant difference, and *** p < 0.001 indicates an extremely significant difference.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	AB + MO3-gjb8
Knockdown Reagent:	MO3-gjb8
Observed In:	lapillus otic vesicle sagitta
Stage:	Protruding-mouth

Phenotype Detail

Acknowledgments

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