FIGURE

Fig. 5

ID

ZDB-FIG-260215-170

Publication

Chen et al., 2026 - GJB2 c.109G > A mutation activating IFI27-mediated mitochondrial apoptosis pathway leading to hereditary non-syndromic hearing loss

Other Figures

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Fig. 5

Sound stimulation behavioral trajectory of zebrafish after GJB2 c.109G > A mutation and knockdown. Videos were recorded using the DanioVision system recording software, and sound stimulation behavioral trajectory analysis experiments were performed (total length 15 min, 30 s sound stimulation (200 Hz, 110 dB sine wave) every 5 min), and the videos were analyzed using EthoVision XT 17 software, A. Generating movement trajectories, B. Calculating the total swimming distance and speed value of zebrafish. n ≥ 10. Each column and bar represent the mean ± SEM. All data were statistically analyzed by one-way ANOVA, * p < 0.05 indicates a significant difference, and *** p < 0.001 indicates an extremely significant difference.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	AB + MO3-gjb8
Condition:	vibration
Knockdown Reagent:	MO3-gjb8
Observed In:	auditory behavior swimming behavior
Stage:	Day 4

Phenotype Detail

Acknowledgments

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