FIGURE

Figure 8

ID

ZDB-FIG-251125-16

Publication

Toso et al., 2025 - Human and zebrafish mineralocorticoid receptors reporter cell assays to assess the activity of chemicals

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Figure 8

hMR and zfMR activities of waste water samples

(A–C) Mineralocorticoid activities of waste water influent and effluent of two urban sites, A and B, were tested in the UG5LN GAL4-hMR and UG5LN-GAL4-zfMR cells. Firstly, influent and effluent of the two sites were tested at the maximal concentration of 3 REF for influents and 6 REF for effluents (A). Secondly, serial dilutions of waste water influents A (B) and B (C) were tested in UG5LN-GAL4-hMR, UG5LN-GAL4-zfMR, and UG5LN-GAL4-hMR (T870L) cells. Sample concentration data are expressed in REF. Results are expressed as the percentage of the maximum luciferase activity induced by 10⁻⁸ M aldosterone. The curves are presented as a non-linear regression; log (REF) versus response.

Data are presented as means ± SD values. n (replicates per experiment) = 4 per group.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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