FIGURE

Fig. 7

ID

ZDB-FIG-251110-7

Publication

Yu et al., 2025 - LPS disrupts erythroid-myeloid balance in zebrafish via Jak2/Stat3-Hif1a signaling

Other Figures

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Fig. 7

Ruxolitinib and hif1a knockdown reduce LPS-induced myeloid differentiation in zebrafish larvae. (A) Neutral red staining for macrophages in larval heads. (B) Fluorescence analysis of Tg(mpeg1:EGFP) in the yolk sac. (C) Sudan Black staining for neutrophils in the yolk sac. (D) Fluorescence analysis of Tg(lyz:EGFP) in the yolk sac. Dotted lines indicate the quantification area. n = replicates per group. ∗∗∗P < 0.001.

Expression Data

Gene:	EGFP
Fish:	ihb20Tg/ihb20Tg nz117Tg/nz117Tg
Conditions:	chemical treatment by injection: lipopolysaccharide chemical treatment by environment: ruxolitinib, chemical treatment by injection: lipopolysaccharide
Anatomical Terms:	yolk syncytial layer macrophage yolk syncytial layer neutrophil
Stage:	Protruding-mouth

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	ihb20Tg/ihb20Tg nz117Tg/nz117Tg AB
Conditions:	chemical treatment by injection: lipopolysaccharide chemical treatment by environment: ruxolitinib, chemical treatment by injection: lipopolysaccharide
Observed In:	head macrophage yolk syncytial layer macrophage yolk syncytial layer neutrophil
Stage:	Protruding-mouth

Phenotype Detail

Acknowledgments

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