FIGURE

Fig. 1

ID

ZDB-FIG-251009-26

Publication

Xiang et al., 2025 - miRNA-130b-3p upregulation impairs osteogenic differentiation in AIS patients by inhibiting the IGF1/ERK pathway

Other Figures

All Figure Page

Back to All Figure Page

Fig. 1

Impaired osteogenic differentiation potential of primary osteoblasts from AIS patients.a. left: Immunohistochemical staining of OPN in the facet joints of the spine from non-AIS control patients (up) and AIS patients (down). Mid: Alkaline Phosphatase staining of primary osteoblasts after 3 days of osteogenic differentiation from non-AIS control patients (up) and AIS patients (down). Right: Alizarin Red S staining of primary osteoblasts after 14 days of osteogenic differentiation from non-AIS control patients (up) and AIS patients (down) b. Quantification of immunohistochemical staining results (n = 10) c. Quantification of Alkaline Phosphatase staining results (n = 10) d. Quantification of Alizarin Red S staining results (n = 10) e. Western blot (WB) results for primary osteoblasts from non-AIS control patients (left) and AIS patients (right) after 3, 7, and 14 days of osteogenic differentiation (n = 4) f. Quantification of RUNX2 protein expression g. Quantification of OCN protein expression **:p<0.01; ***:p<0.001

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Cell. Mol. Life Sci.