FIGURE

Fig. 5

ID

ZDB-FIG-251009-30

Publication

Xiang et al., 2025 - miRNA-130b-3p upregulation impairs osteogenic differentiation in AIS patients by inhibiting the IGF1/ERK pathway

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Fig. 5

miRNA-130b-3p inhibits ERK1/2 phosphorylation by downregulating IGF1 expression levels.a-e. Protein expression levels of IGF1, IGF1R, P-IGF1R, ERK1/2, P-ERK1/2, and GAPDH in primary osteoblasts from AIS and control group patients (n = 3) f-h. Protein expression levels of IGF1, IGF1R, P-IGF1R, ERK1/2, P-ERK1/2, and GAPDH in primary osteoblasts from the control group treated with miR-130b mimic and IGF1 recombinant protein (n = 3) ***:p<0.001; **:p<0.01; *:p<0.05

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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