Fig. 6
- ID
- ZDB-FIG-250814-107
- Publication
- Hsu et al., 2025 - Single cell transcriptomes of zebrafish germline reveal progenitor types and feminization by Foxl2l
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- Fig. 4
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Schematic illustration of the function of Foxl2l during germ cell development in juvenile gonad. During the sex determination period, germ cells develop following the trajectory from germline stem cell (GSC), GSC to progenitor (G–P) transition, early progenitor (Prog-E), committed progenitor (Prog-C), late progenitor (Prog-L) to the female meiotic stage. Foxl2l is essential for the maturation of Prog-C and the ensuing Prog-L development. In foxl2l mutant, germ cells are arrested at Prog-C. Some mutant Prog-C cells (mProg-C) express nanos2. The absence of functional Foxl2l eventually triggers male development. Blue symbols indicate alternative development in foxl2l mutants. Red arrows indicate the developmental trajectory of females. |