FIGURE

Figure 1

ID

ZDB-FIG-250701-38

Publication

Rosa et al., 2025 - Evaluating TnP as a Potential Therapeutic Agent for Retinopathy in Zebrafish Models

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Figure 1

Retinopathy in zebrafish larvae. Retinopathy was induced in 3 dpf larvae through exposure to E2 0.5x medium at 28 °C with 0.5 mM cobalt chloride (CoCl₂) for 72 h (A). Independent group of 3 dpf larvae was exposed to intense light at 8000 lux for 24 h (LIRD) (B). Larvae maintained at 28 °C in E2 0.5x medium only and under natural light were considered negative controls. Immediately after stimulation, all groups of larvae were evaluated for their visual–motor response (C,D) and distance traveled (E) and were subsequently killed and processed for histological analysis and H&E staining (F). * p < 0.05 compared to control group. Bars represent mean ± SEM. Dots represent individual data points. RGL: retinal ganglion layer; IPL: inner plexiform layer; INL: inner nuclear layer; OPL: outer plexiform layer; ONL: outer plexiform layer; OSL: outer segment layer; RPE: retinal pigment epithelium.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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