FIGURE

FIGURE 1

ID

ZDB-FIG-250627-118

Publication

Ikeda et al., 2025 - Transcriptome Analysis Suggested Striking Transition Around the End of Epiboly in the Gene Regulatory Network Downstream of the Oct4-Type POU Gene in Zebrafish Embryos

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FIGURE 1

Microarray analysis of the altered transcriptome due to suppression of endogenous pou5f3 in zebrafish embryos. (A–D) Venn diagrams showing the numbers of genes/probes (total number, 15,617) whose expression was downregulated (A, B) or upregulated (C, D) by en‐pou5f3 induction at 90% epiboly (left) or 3‐ss (right), respectively. (A, C) All genes whose expression was judged to have been significantly affected by the Wilcoxon signed‐rank test (upregulated, p < 0.0025; downregulated, p > 0.9975). (B, D) Genes whose expression was evidently affected by en‐pou5f3 induction by twice or more (signal log ratio, > 1 or < −1). E. Alteration of bHLH‐O gene expression due to en‐pou5f3 induction. Signal log ratios showing changes in expression levels, obtained by the microarray, are shown with a heat map for the two induction stages. The genes are arranged based on the signal log ratios at 90% epiboly. Green indicates downregulation, and magenta indicates upregulation. Blue letters indicate her‐related genes that function in a Notch‐independent manner, whereas the genes shown in red are Notch‐dependent.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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