FIGURE

Fig. 5

ID

ZDB-FIG-250529-30

Publication

Yang et al., 2025 - Direct regulation of Per2 by Roraa: insights into circadian and metabolic interplay in zebrafish

Other Figures

All Figure Page

Back to All Figure Page

Fig. 5

Whole-body overexpression of roraa disrupts the behavioral rhythms of zebrafish. A Activity change curves for WT and Tg(hsp70 l;CG2) after heat shock at 37 °C. B–D Analysis results of the period, phase, and amplitude. The R package MetaCycle was used for rhythmic analysis of the behavior data, and there were no significant differences in the activity period between WT and roraa−/−; however, the activity phase of roraa−/− zebrafish was advanced by approximately 5 h, and the activity amplitude was significantly lower than that of WT zebrafish. E Changes in the expression of the core clock genes bmal1b, clock1a, cry1aa, and per2 in WT and Tg(hsp70 l;CG2) after heat shock at 37 °C. The black curve represents activity changes in WT, whereas the green curve represents activity changes in Tg(hsp70 l;CG2). The method for difference analysis was Student's t test; ns indicates p > 0.05, * indicates p < 0.05

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Cell. Mol. Life Sci.