FIGURE

Fig 4

ID

ZDB-FIG-250515-12

Publication

Blair et al., 2025 - Forward genetic screen in zebrafish identifies new fungal regulators that limit host-protective Candida-innate immune interaction

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Fig 4

Mutants grouped by altered innate immune response. Mutant–phagocyte interactions were scored at 4–6 hpi, relative to wild-type fungi–phagocyte interactions in the same experiment, as to immune cell number and phagocytosis efficiency traits. Group I mutants had lower numbers of recruited phagocytes and better phagocytosis and containment. Group II mutants had fewer recruited phagocytes and unchanged phagocytosis efficiency. The Group III mutant had no change in phagocyte recruitment but better phagocytosis. The Group IV mutant had higher phagocyte recruitment and better phagocytosis. “Down” or “up” text indicates the direction of differential immune response, bold lettering indicates P < 0.05, and regular lettering indicates 0.2 < P < 0.05. Heavy shading indicates strong effect size; light shading indicates moderate effect size.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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