FIGURE

Fig 2

ID
ZDB-FIG-250321-10
Publication
Nonarath et al., 2025 - The USH3A causative gene clarin1 functions in Müller glia to maintain retinal photoreceptors
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Fig 2

clrn1-/- zebrafish present with an altered UV cone mosaic beginning at 8 mpf.

En face images of the UV cone mosaic were segmented from OCT scans, a higher magnification ventro-temporal region of interest (ROI) was selected (a’-h’) and processed for Voronoi overlay analysis (a”-h”) in wild-type at (a) 4, (b) 8, (c) 12, and (d) 24 mpf, as well as clrn1-/- zebrafish at (e) 4, (f) 8, (g) 12, and (h) 24 mpf. Quantification of the UV cone mosaic regularity revealed statistically significant differences in (i) intercell distance regularity, (j) number of neighbors regularity and, (k) the Voronoi area regularity at 8 mpf in clrn1-/- zebrafish compared to wild-type. (*p<0.05, **p<0.01, ****p<0.001; Two-way ANOVA).

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
Acknowledgments
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