FIGURE

Fig 7

ID

ZDB-FIG-250321-15

Publication

Nonarath et al., 2025 - The USH3A causative gene clarin1 functions in Müller glia to maintain retinal photoreceptors

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Fig 7

Apical processes of Müller glia and calyceal processes of cone photoreceptors are disorganized in clrn1^-/- retina.

Transverse sections from 7 dpf (a) wild-type and (b,c) clrn1^-/- mutant zebrafish each expressing the Tg(gfap:GFP); Tg(gnat2:Lifeact-mCherry) transgenes highlighting either (b) moderately or (c) more severely altered Müller glia apical microvilli projections (b’,c’) and cone-specific actin structures (b,” c”) in clrn1^-/- mutants. (d) Cartoon showing the area imaged (red bar). Scale bar = 10 µm. OLM, Outer limiting membrane; OPL, Outer plexiform layer. Schematic in (d) created in BioRender under License: https://BioRender.com/x12n534.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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