FIGURE

Figure 7

ID

ZDB-FIG-250320-19

Publication

Manickam et al., 2025 - Paving the way for better ototoxicity assessments in cisplatin therapy using more reliable animal models

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Figure 7

Clinical cisplatin treatment affects stimulus-dependent swimming behavior. (A) Experimental setup for the behavioral studies. (B) Cumulative distance traveled (CDT) by the zebrafish larva during the four stimulus periods (top) or over the 4 min experimental period (bottom). Results are expressed as mean +/− SD. Circles represent individual animals. Statistical analysis: Student’s t test. ***p < 0.001. (C) Track visualization of the distance covered over the 4 min period by larva treated with vehicle or clinical cisplatin. Scale bar = 1.25 cm. Biorender was used to generate part of this figure.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT
Condition:	chemical treatment by environment: cisplatin
Observed In:	mechanosensory behavior swimming behavior
Stage Range:	Day 5 to Day 6

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front. Cell. Neurosci.