FIGURE

Fig. 3

ID

ZDB-FIG-250304-3

Publication

Chen et al., 2025 - NDUFB7 mutations cause brain neuronal defects, lactic acidosis, and mitochondrial dysfunction in humans and zebrafish

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Fig. 3

Knockdown of Ndufb7 changes the sizes of brain ventricles.

We microinjected 1-cell stage zebrafish embryos without (untreated) or with indicated reagents and photographed them under a stereomicroscope at 48 hours post-fertilization. A Representative images for each treatment are presented. The ventricles are enclosed in red and white dotted lines for the midbrain and hindbrain, respectively. The area of the ventricle was measured in pixels using the Image J software. All data are shown in a scatter plot with mean ± standard error of the mean (SEM) for each treatment shown at the bottom of each column for B midbrain and C hindbrain, respectively, from three independent experiments. **p < 0.01; ***p < 0.001; ****p < 0.0001.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	AB + MO1-ndufb7
Condition:	chemical treatment by injection: Mitoquinone
Knockdown Reagent:	MO1-ndufb7
Observed In:	fourth ventricle tectal ventricle
Stage:	Long-pec

Phenotype Detail

Acknowledgments

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