FIGURE
Fig. 5
- ID
- ZDB-FIG-250304-25
- Publication
- Sebo et al., 2025 - Activation of Wnt/β-catenin in neural progenitor cells regulates blood-brain barrier development and promotes neuroinflammation
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Fig. 5
Activated Wnt/?-catenin signaling in NPCs decreases tip cell migration. Lateral still frames from time-lapse confocal microscopy of gfap:rtTA, TRE:?-cat*-EGFP larvae treated with indicated Dox concentrations. Snapshots are at 4-h intervals over 16 h of acquisition beginning at the onset of CNS angiogenesis (30 hpf). Magnified frames (4?×?Zoom) highlight the hindbrain region bounded ventrally by the primordial hindbrain channels. Stereotypical tip cells are indicated by white asterisks. Stereotypical filipodia are indicated by red arrowheads. See supplementary videos 4, 5 for more detail. |
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
Phenotype Detail
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