FIGURE

Figure 5.

ID
ZDB-FIG-250214-27
Publication
Wawruszak et al., 2025 - Selisistat, a SIRT1 inhibitor, enhances paclitaxel activity in luminal and triple-negative breast cancer: in silico, in vitro, and in vivo studies
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Figure 5.

The percentage of zebrafish embryos initiated 2 days post-fertilization (dpf) that survived after 1, 2 or 3 days of treatment with indicated concentrations of (a) EX527, (b) PAX and (c) EX527:PAX (IC50 mix). IC50 drug doses refer to the effective therapeutic concentrations were determined earlier by the in vitro MTT assay. Analyses were performed in triplicates, n = 15 per group. Data are presented as mean ± standard deviation of the mean (SD), ***p < 0.001 determined by one-way ANOVA, Tukey’s post-hoc test.

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ J Enzyme Inhib Med Chem