FIGURE

Figure 3.

ID
ZDB-FIG-250214-25
Publication
Wawruszak et al., 2025 - Selisistat, a SIRT1 inhibitor, enhances paclitaxel activity in luminal and triple-negative breast cancer: in silico, in vitro, and in vivo studies
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Figure 3.

Evaluation of single or combined drug-mediated effects on the proliferation of (a) MCF7, (b) T47D, (c) MDA-MB-231, (d) BT-549, (e) MDA-MB-468 BC cells in the BrdU assay. BC cells were exposed for 48 h to 1/2 and IC50 PAX, EX527 or 1:1 PAX:EX527 (1/2 and IC50 mix). The data are presented as the mean ± standard deviation (±SD) of the mean. *p < 0.05, **p < 0.01, ***p < 0.001 by one-way ANOVA, Tukey’s post-hoc test.

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ J Enzyme Inhib Med Chem