FIGURE

Fig. 2

ID
ZDB-FIG-241017-32
Publication
Armistead et al., 2024 - A sphingolipid rheostat controls apoptosis versus apical cell extrusion as alternative tumour-suppressive mechanisms
Other Figures
All Figure Page
Back to All Figure Page
Fig. 2

Cell death in hai1afr26 mutants is caspase-dependent and tp53-independent.

ah Apoptotic cells in the caudal fin fold of 4 dpf embryos, immunostained for aCasp3 (red), p63 (green) and DAPI (blue), with tp53 mutation or upon treatment with ZDEVD-FMK to inhibit apoptosis. Scale bar = 50 μm. i Quantification of the numbers of aCasp3-positive cells in the tail fins of embryos, normalised to fin area. Means were compared using one-way ANOVA with post-hoc Tukey’s multiple comparison test. j Survival curves showing the effects of tp53 mutation or ZDEVD-FMK treatment on embryo viability.

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Cell Death Dis.