FIGURE

Figure S5.

ID

ZDB-FIG-240821-44

Publication

Karampelias et al., 2024 - Examining the liver-pancreas crosstalk reveals a role for the molybdenum cofactor in β-cell regeneration

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Figure S5.

Gene expression profile of the molybdenum biosynthetic pathway in zebrafish.

(A, B, C, D, E, F, G, H, I, J, K, L) Gene expression changes (fold change values) at the end of the regenerative period in Tg(ins:flag-NTR);Tg(fabp10a:smocs2) 6 dpf zebrafish larvae, that is, for genes involved in the molybdenum cofactor biosynthetic pathway (A, B, C, D, E, F), enzymes using Moco (G, H, I, J), and key glycolytic/gluconeogenic enzymes (K, L). (C)n = 4. *P = 0.0286, a non-parametric Mann–Whitney test for (C). Data are presented as mean values ± SEM. (M, N, O, P, Q, R, S, T, U, V, W, X) Gene expression changes (fold change values) after β-cell ablation 3–4 dpf in Tg(ins:flag-NTR) zebrafish larvae and control or sodium molybdate treatment 4–6 dpf, that is, for genes involved in the molybdenum cofactor biosynthetic pathway (M, N, O, P, Q, R), enzymes using Moco (S, T, U, V), and key glycolytic/gluconeogenic enzymes (W, X). n = 4. Data are presented as mean values ± SEM.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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