FIGURE

Fig. 6

ID

ZDB-FIG-240620-49

Publication

Gauthier et al., 2024 - Therapeutic antibody engineering for efficient targeted degradation of membrane proteins in lysosomes

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Fig. 6

Increased anti-migration and anti-proliferative effects of CTX-AMFA. HaCaT cells were treated with 10 nM CTX or CTX-AMFA for 72 h. A wound healing test was realized and the scratch area was monitored at 24, 48 and 72 h to assess the cell migration and proliferation. (A) Wound healing test at 0 h, 24 h, 48 h and 72 h after treatment. (B) Increment in the free area by CTX and CTX-AMFA. Free areas were quantified at different time points and compared to the area at time 0 h. Results are presented as the percentage of the free area variation in mAb treated cells over time compared to the free area variation in untreated control cells. Mean � SD. Student?s t-test: ** p value < 0.01.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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