FIGURE

Fig 7

ID

ZDB-FIG-240614-69

Publication

Belt et al., 2024 - Myeloid Targeted Human MLL-ENL and MLL-AF9 Induces cdk9 and bcl2 Expression in Zebrafish Embryos

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Fig 7

Dose dependent effect of Venetoclax and Flavopiridol on myelopoiesis.

Embryos were treated with 100nM or 500nM of Venetoclax (A-M) or 100nM and 500nM Flavopiridol (N-Z) and assessed for expression of lyz (A-C, N-P, N = 10), mpx (D-F, Q-S, N = 16–19), mpeg (G-I, T-V, N = 20), and cmyb (J-L, W-Y, N = 16–20) by counting the number of positive cells expressing each marker in the CHT (M,Z). Arrows indicate marker gene expression in the CHT. Statistical analysis was conducted using one-way ANOVA followed by Tukey HSD. * p<0.05, ** p<0.01, NS = not significant. Anterior to the left.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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