FIGURE

Fig. 11

ID

ZDB-FIG-240521-34

Publication

Chakraborty et al., 2024 - Inhibition of NF-κB-Mediated Proinflammatory Transcription by Ru(II) Complexes of Anti-Angiogenic Ligands in Triple-Negative Breast Cancer

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Fig. 11

Cell viability comparison between HMEC-1 and MDA-MB-231 cell lines upon treatment with various doses of L3, L5, 6, and 12 for 72 h. (A) L3 showing lower toxicity toward HMEC-1 compared to MDA-MB-231. (B) L5 showing closely similar toxicity profile toward HMEC-1 and MDA-MB-231. (C) Complexes 6 and 12 showing a significantly lower toxicity toward HMEC-1 compared to MDA-MB-231 and unable to kill beyond 50% even at a 100 μM dose. A comparison of the data for L5 in (B) and its complex 12 in (C) shows that the ligand is more toxic in vitro than the complex on HMEC-1 [the x-axis denotes the logarithmic concentration (nanomolar) of the compounds].

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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