FIGURE

Fig. 6

ID

ZDB-FIG-240521-29

Publication

Chakraborty et al., 2024 - Inhibition of NF-κB-Mediated Proinflammatory Transcription by Ru(II) Complexes of Anti-Angiogenic Ligands in Triple-Negative Breast Cancer

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Fig. 6

(A) Histogram depicting the dose-dependent (5 and 10 μM) induction of apoptosis by complexes 6 and 12 in MDA-MB-231 cells after 16 h of treatment, as analyzed through flow cytometry. (B) Flow cytometry analysis of the mitochondrial depolarization using JC-1 dye following treatment with 5 and 10 μM of 6 or 12 for 8, 16, and 36 h incubation periods reveal a notable, dose- and time-dependent elevation in monomeric JC-1 fluorescence. This observation is indicative of enhanced mitochondrial membrane depolarization, highlighting the intricate relationship between treatment, dosage, time, and mitochondrial function.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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