ZFIN Image: Chakraborty et al., 2024, Fig. 6

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Figure Caption

Fig. 6 (A) Histogram depicting the dose-dependent (5 and 10 μM) induction of apoptosis by complexes 6 and 12 in MDA-MB-231 cells after 16 h of treatment, as analyzed through flow cytometry. (B) Flow cytometry analysis of the mitochondrial depolarization using JC-1 dye following treatment with 5 and 10 μM of 6 or 12 for 8, 16, and 36 h incubation periods reveal a notable, dose- and time-dependent elevation in monomeric JC-1 fluorescence. This observation is indicative of enhanced mitochondrial membrane depolarization, highlighting the intricate relationship between treatment, dosage, time, and mitochondrial function.

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