FIGURE

Figure 7

ID

ZDB-FIG-240513-60

Publication

Song et al., 2024 - Functional and Genetic Analyses Unveil the Implication of CDC27 in Hemifacial Microsomia

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Figure 7

Comparative analysis of chondrocyte morphology in cdc27 mutants and control siblings using fluorescent WGA staining. This figure illustrates the results of fluorescent wheat germ agglutinin (WGA) staining at 4 days post-fertilization (dpf), showcasing the craniofacial cartilage formation in both control siblings and cdc27^−/− mutant embryos. In the control siblings, the craniofacial cartilage demonstrates a highly consistent and stereotypical shape, akin to a “stack of pennies” where elongated and slender chondrocytes are meticulously arranged in layers, forming the individual cartilage elements. In stark contrast, the cdc27^−/− embryos exhibit significantly altered chondrocyte morphology: the chondrocytes within the cartilage are noticeably smaller and the overall cartilage structures are markedly deformed, deviating substantially from the organized arrangement seen in the control siblings.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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