FIGURE

Figure 6

ID

ZDB-FIG-240327-26

Publication

Daurat et al., 2024 - Engineered therapeutic antibodies with mannose 6-phosphate analogues as a tool to degrade extracellular proteins

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Figure 6

In vivo efficacy of BVZ-AMFA2_(n=5) tumor angiogenesis in the CAM of chick embryos. After injection of 10⁶ MDA-MB-231 human cancer cells at day 9 in CAM, embryos were treated with 1 mg.kg^-1 BVZ or BVZ-AMFA2_(n=5) or vehicle at days 10, 12, 13 and 15. The representative pictures of control and embryos treated with BVZ or BVZ-AMFA2_(n=5) at day 16 are presented and the number of blood vessels of size > 130 µm surrounding the tumor area are indicated by the arrows (A). The mean ± SD of vessels counted in 7 embryos treated with BVZ or BVZ-AMFA2_(n=5) and in 7 vehicle-treated embryos are presented (B). Tukey’s test: * p value < 0.05.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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