FIGURE

Figure 4

ID

ZDB-FIG-240327-24

Publication

Daurat et al., 2024 - Engineered therapeutic antibodies with mannose 6-phosphate analogues as a tool to degrade extracellular proteins

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Figure 4

Neutralization of the cellular activities of antigens with mAb-AMFA. Murine fibroblasts L929 were treated with 5 ng.mL^-1 TNF-α and increasing doses of IFX or IFX-AMFA1 (A). HUVECs were treated with 50 ng.mL^-1 of VEGF and increasing doses of BVZ or BVZ-AMFA1 (B). The neutralization of antigens effect was evaluated by a cell viability assay by incubating cells with MTT. Results are expressed as a percentage ± SD of control cells without mAb treatment. Student’s T-test: * p value < 0.05; ** p value < 0.01.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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